Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 2/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11823334 | 0.88 | MCL1 (0.44) | DAOMEN1KMT2ALMNARAB9A | |
| SCHEMBL11825039 | 0.87 | DAO (0.53) | DAONR4A2EPHX1SRD5A2GFER | |
| SCHEMBL11826895 | 0.87 | PTPRC (0.46) | DAOMEN1KMT2ANR4A2LMNA | |
| SCHEMBL11820578 | 0.78 | ALDH1A1 (0.45) | DAOMEN1KMT2ANR4A2SRD5A2 | |
| SCHEMBL11816938 | 0.78 | GFER (0.44) | DAOMEN1KMT2AEPHX1LMNA | |
| SCHEMBL11821491 | 0.78 | MEN1 (0.45) | DAOMEN1KMT2AEPHX1LMNA | |
| SCHEMBL11820346 | 0.78 | NR4A2 (0.47) | DAOMEN1KMT2ANR4A2EPHX1 | |
| SCHEMBL11818815 | 0.78 | MRGPRX4 (0.42) | MEN1KMT2ANR4A2EPHX1MRGPRX4 | |
| SCHEMBL11820185 | 0.77 | AKR1C3 (0.43) | MEN1KMT2ALMNARAB9AGFER | |
| SCHEMBL11810807 | 0.77 | ALDH1A1 (0.41) | MEN1KMT2ALMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |