Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | TOP2A | P11388 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11823334 | 0.85 | MCL1 (0.44) | AKR1C3ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL11820625 | 0.80 | ALDH1A1 (0.47) | AKR1C3ALDH1A1MAPK1HPGDMEN1 | |
| SCHEMBL11818278 | 0.79 | L3MBTL1 (0.54) | ALDH1A1MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL11820227 | 0.78 | TRPV1 (0.46) | ALDH1A1MAPK1HPGDMEN1KMT2A | |
| SCHEMBL11818047 | 0.78 | CA2 (0.42) | AKR1C3ALDH1A1MAPK1HPGDTAS2R14 | |
| SCHEMBL11826895 | 0.77 | PTPRC (0.46) | AKR1C3HPGDTAS2R14MEN1KMT2A | |
| SCHEMBL11821945 | 0.77 | DAO (0.47) | ALDH1A1MEN1KMT2ALMNARAB9A | |
| SCHEMBL11810807 | 0.74 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ALMNAPOLB | |
| SCHEMBL732949 | 0.72 | LCK (0.57) | ALDH1A1MAPK1HPGDMEN1KMT2A | |
| SCHEMBL18513400 | 0.72 | LCK (0.52) | ALDH1A1MAPK1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |