Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.46 |
| ▸ | PTPRG | P23470 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.42 |
| ▸ | DAO | P14920 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11823334 | 0.88 | MCL1 (0.44) | PTPRCPLA2G1BMAPTATG4BAKR1C3 | |
| SCHEMBL11821945 | 0.87 | DAO (0.47) | MRGPRX4PLA2G1BMAPTATG4BDAO | |
| SCHEMBL11822234 | 0.79 | L3MBTL1 (0.57) | ARMRGPRX4MAPTLMNAL3MBTL1 | |
| SCHEMBL11818815 | 0.78 | MRGPRX4 (0.42) | MRGPRX4PLA2G1BMAPTATG4BNR4A2 | |
| SCHEMBL11820185 | 0.77 | AKR1C3 (0.43) | AKR1C3TAS2R14LMNAL3MBTL1POLB | |
| SCHEMBL11818315 | 0.77 | AKR1C3 (0.54) | PTPRCPTPRGARMRGPRX4MAPT | |
| SCHEMBL11810807 | 0.77 | ALDH1A1 (0.41) | MAPTLMNAPOLBMEN1KMT2A | |
| SCHEMBL13802466 | 0.77 | MRGPRX4 (0.63) | PTPRCPTPRGARMRGPRX4PLA2G1B | |
| SCHEMBL693069 | 0.75 | RXRA (0.57) | PTPRCPTPRGARMRGPRX4MAPT | |
| SCHEMBL11825039 | 0.72 | DAO (0.53) | MRGPRX4PLA2G1BMAPTATG4BDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |