Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11821945 | 0.88 | DAO (0.47) | LMNAMEN1KMT2APLA2G1BMAPT | |
| SCHEMBL11826895 | 0.88 | PTPRC (0.46) | HPGDLMNAPTPRCMEN1KMT2A | |
| SCHEMBL11820185 | 0.85 | AKR1C3 (0.43) | HPGDLMNAMEN1KMT2APOLB | |
| SCHEMBL11810807 | 0.85 | ALDH1A1 (0.41) | LMNAMEN1KMT2AMAPTPOLB | |
| SCHEMBL11820578 | 0.81 | ALDH1A1 (0.45) | MCL1BCL2A1HPGDLMNAPTPRC | |
| SCHEMBL11822961 | 0.80 | ALDH1A1 (0.49) | MCL1BCL2A1HPGDLMNAMEN1 | |
| SCHEMBL11818108 | 0.79 | PTPRZ1 (0.40) | HPGDLMNAMEN1KMT2APOLB | |
| SCHEMBL11818815 | 0.79 | MRGPRX4 (0.42) | MCL1BCL2A1HPGDMEN1KMT2A | |
| SCHEMBL11819988 | 0.79 | LMNA (0.46) | MCL1BCL2A1HPGDLMNAPTPRC | |
| SCHEMBL11816930 | 0.79 | TAS2R14 (0.59) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |