Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.39 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | UGT1A7 | Q9HAW7 | 1/20 | 0.39 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 6/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11823574 | 0.96 | MAPT (0.44) | ALDH1A1MAPTVCAM1CA2SMN1; SMN2 | |
| SCHEMBL11821357 | 0.91 | CNR2 (0.48) | ALDH1A1MAPTVCAM1CA2SMN1; SMN2 | |
| SCHEMBL11822163 | 0.91 | CA2 (0.47) | ALDH1A1MAPTVCAM1CA2SMN1; SMN2 | |
| SCHEMBL11818580 | 0.91 | CA2 (0.47) | ALDH1A1MAPTVCAM1CA2SMN1; SMN2 | |
| SCHEMBL11816329 | 0.90 | CNR2 (0.49) | ALDH1A1MAPTVCAM1CA2SMN1; SMN2 | |
| SCHEMBL11823209 | 0.87 | VCAM1 (0.47) | ALDH1A1MAPTVCAM1SMN1; SMN2CA12 | |
| SCHEMBL11820805 | 0.86 | CA2 (0.48) | ALDH1A1MAPTVCAM1CA2SMN1; SMN2 | |
| SCHEMBL11819740 | 0.86 | VCAM1 (0.40) | ALDH1A1MAPTVCAM1CA2SMN1; SMN2 | |
| SCHEMBL11819726 | 0.85 | LMNA (0.45) | ALDH1A1MAPTVCAM1CA2SMN1; SMN2 | |
| SCHEMBL11819921 | 0.84 | CNR2 (0.48) | ALDH1A1MAPTVCAM1CA2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |