Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 3/20 | 0.40 |
| ▸ | MMP2 | P08253 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11819669 | 0.96 | ALDH1A1 (0.51) | VCAM1ALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL11821357 | 0.88 | CNR2 (0.48) | VCAM1ALDH1A1MAPTLMNACA12 | |
| SCHEMBL11818580 | 0.88 | CA2 (0.47) | VCAM1ALDH1A1MAPTKMT2ACA12 | |
| SCHEMBL11822163 | 0.88 | CA2 (0.47) | VCAM1ALDH1A1MAPTKMT2ACA12 | |
| SCHEMBL11823057 | 0.87 | ALDH1A1 (0.41) | VCAM1ALDH1A1MAPTCA12CA9 | |
| SCHEMBL11816329 | 0.87 | CNR2 (0.49) | VCAM1ALDH1A1MAPTLMNAHTT | |
| SCHEMBL11816192 | 0.86 | MAPT (0.48) | VCAM1ALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL11821697 | 0.85 | ALDH1A1 (0.49) | ALDH1A1MAPTKMT2AHTTMAPK1 | |
| SCHEMBL11820805 | 0.84 | CA2 (0.48) | VCAM1ALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL11819726 | 0.83 | LMNA (0.45) | VCAM1ALDH1A1MAPTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |