Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PTPRG | P23470 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11821631 | 0.91 | CA2 (0.49) | VCAM1CA2MAPTCA4HTT | |
| SCHEMBL11825881 | 0.90 | TAS2R14 (0.43) | VCAM1CA2MAPTCA4HTT | |
| SCHEMBL11823574 | 0.88 | MAPT (0.44) | VCAM1CA2MAPTCA4HTT | |
| SCHEMBL11816192 | 0.87 | MAPT (0.48) | VCAM1MAPTHTTALDH1A1KDM4E | |
| SCHEMBL11823057 | 0.86 | ALDH1A1 (0.41) | VCAM1CA2MAPTCA4ALDH1A1 | |
| SCHEMBL11821552 | 0.84 | CA2 (0.42) | CA2CA4HTTPTPRGALDH1A1 | |
| SCHEMBL11825334 | 0.83 | KMT2A (0.43) | VCAM1CA2CA4HTTPTPRG | |
| SCHEMBL11815898 | 0.83 | PTPRG (0.46) | VCAM1CA2CA4PTPRGLMNA | |
| SCHEMBL11820805 | 0.78 | CA2 (0.48) | VCAM1CA2MAPTCA4ALDH1A1 | |
| SCHEMBL11819726 | 0.77 | LMNA (0.45) | VCAM1CA2MAPTCA4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |