Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | BMP1 | P13497 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 3/20 | 0.40 |
| ▸ | MMP2 | P08253 | 3/20 | 0.40 |
| ▸ | MMP9 | P14780 | 3/20 | 0.40 |
| ▸ | MMP8 | P22894 | 3/20 | 0.40 |
| ▸ | MMP13 | P45452 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11819669 | 0.88 | ALDH1A1 (0.51) | MAPTALDH1A1VCAM1HTTBMP1 | |
| SCHEMBL11821631 | 0.88 | CA2 (0.49) | MAPTALDH1A1VCAM1HTTKMT2A | |
| SCHEMBL11825881 | 0.87 | TAS2R14 (0.43) | MAPTALDH1A1VCAM1HTTKMT2A | |
| SCHEMBL11819740 | 0.87 | VCAM1 (0.40) | MAPTALDH1A1KDM4EVCAM1HTT | |
| SCHEMBL11823209 | 0.86 | VCAM1 (0.47) | MAPTALDH1A1VCAM1HTTBMP1 | |
| SCHEMBL11821697 | 0.85 | ALDH1A1 (0.49) | MAPTALDH1A1HTTKMT2ACYP3A4 | |
| SCHEMBL11815898 | 0.81 | PTPRG (0.46) | VCAM1KMT2AMEN1SMN1; SMN2CA12 | |
| SCHEMBL11825334 | 0.81 | KMT2A (0.43) | ALDH1A1KDM4EVCAM1HTTBMP1 | |
| SCHEMBL11824126 | 0.77 | KMT2A (0.59) | MAPTALDH1A1HTTKMT2ACYP3A4 | |
| SCHEMBL3174472 | 0.76 | VCAM1 (0.63) | MAPTALDH1A1KDM4EVCAM1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |