Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11816465 | 0.81 | KDM5A (0.41) | MRGPRX4ARMEP1BRXFP1KAT6A | |
| SCHEMBL11822411 | 0.79 | MRGPRX4 (0.40) | MRGPRX4MEP1BRXFP1KAT6APTPRC | |
| SCHEMBL11818815 | 0.79 | MRGPRX4 (0.42) | MRGPRX4MEP1BMEN1KMT2AKDM4E | |
| SCHEMBL11818479 | 0.79 | CA2 (0.46) | MRGPRX4ARMEN1KMT2AALDH1A1 | |
| SCHEMBL11820346 | 0.73 | NR4A2 (0.47) | MRGPRX4ARMEN1KMT2AALDH1A1 | |
| SCHEMBL11820018 | 0.72 | CA2 (0.53) | MEN1KMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL11818248 | 0.71 | CA2 (0.43) | MRGPRX4ARMEN1KMT2AKDM4E | |
| SCHEMBL11821491 | 0.71 | MEN1 (0.45) | MEN1KMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL29937265 | 0.71 | F2 (0.53) | MEP1BMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL1449037 | 0.71 | F2 (0.53) | MEP1BMEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |