Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | PTPRG | P23470 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11818479 | 0.91 | CA2 (0.46) | CA2CA4ALDH1A1RXFP1KMT2A | |
| SCHEMBL11820018 | 0.88 | CA2 (0.53) | CA2CA4ALDH1A1RXFP1KMT2A | |
| SCHEMBL11821491 | 0.87 | MEN1 (0.45) | CA2CA4ALDH1A1KMT2AMEN1 | |
| SCHEMBL11816258 | 0.86 | CYP1A2 (0.46) | CA2CA4ALDH1A1TAS2R14PTGDR2 | |
| SCHEMBL11825522 | 0.84 | ALDH1A1 (0.46) | CA2CA4ALDH1A1KMT2AMEN1 | |
| SCHEMBL11817200 | 0.83 | ALDH1A1 (0.53) | CA2CA4ALDH1A1TAS2R14KMT2A | |
| SCHEMBL10741558 | 0.81 | FKBP1A (0.47) | ALDH1A1PTPRGL3MBTL1HPGDLMNA | |
| SCHEMBL11817917 | 0.81 | PTPRG (0.47) | CA2CA4KMT2AMEN1PTPRG | |
| SCHEMBL11814899 | 0.81 | PPARD (0.43) | CA2CA4PTPRGL3MBTL1ACLY | |
| SCHEMBL11817140 | 0.81 | CA2 (0.42) | CA2CA4ALDH1A1RXFP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |