Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.42 |
| ▸ | PTPRG | P23470 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 2/20 | 0.39 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11820018 | 0.93 | CA2 (0.53) | CA2CA4RXFP1PTPRGEPAS1 | |
| SCHEMBL11818248 | 0.91 | CA2 (0.43) | CA2CA4RXFP1PTPRGAR | |
| SCHEMBL11821491 | 0.91 | MEN1 (0.45) | CA2CA4KCNQ3KCNQ2ALDH1A1 | |
| SCHEMBL11825522 | 0.88 | ALDH1A1 (0.46) | CA2CA4ALDH1A1MEN1KMT2A | |
| SCHEMBL11816258 | 0.88 | CYP1A2 (0.46) | CA2CA4PTPRGEPAS1ALDH1A1 | |
| SCHEMBL11816465 | 0.88 | KDM5A (0.41) | CA2CA4RXFP1PTPRGAR | |
| SCHEMBL11814899 | 0.84 | PPARD (0.43) | CA2CA4PTPRGEPAS1 | |
| SCHEMBL11817140 | 0.84 | CA2 (0.42) | CA2CA4RXFP1PTPRGEPAS1 | |
| SCHEMBL11817749 | 0.84 | PTPRG (0.44) | CA2CA4RXFP1PTPRGEPAS1 | |
| SCHEMBL11817917 | 0.84 | PTPRG (0.47) | CA2CA4PTPRGARMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |