Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.46 |
| ▸ | HTR1A | P08908 | 5/20 | 0.46 |
| ▸ | HTR2A | P28223 | 4/20 | 0.46 |
| ▸ | DRD3 | P35462 | 4/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.46 |
| ▸ | DRD1 | P21728 | 2/20 | 0.46 |
| ▸ | DRD5 | P21918 | 2/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11823642 | 0.94 | SLC2A1 (0.46) | DRD2HTR1AHTR2ADRD3SIGMAR1 | |
| SCHEMBL11826952 | 0.89 | HTR1A (0.48) | DRD2HTR1AHTR2ASIGMAR1TMEM97 | |
| SCHEMBL11552756 | 0.85 | DRD2 (0.48) | DRD2HTR1AHTR2ADRD3DRD1 | |
| SCHEMBL11822913 | 0.83 | SIGMAR1 (0.47) | DRD2HTR1AHTR2ASIGMAR1CCR3 | |
| SCHEMBL11828423 | 0.81 | HTR1A (0.52) | DRD2HTR1AHTR2ADRD3SIGMAR1 | |
| SCHEMBL11827870 | 0.81 | SIGMAR1 (0.58) | HTR1ASIGMAR1 | |
| SCHEMBL11834202 | 0.79 | DRD2 (0.61) | DRD2HTR1AHTR2ADRD3SIGMAR1 | |
| SCHEMBL11829630 | 0.78 | SIGMAR1 (0.56) | DRD2HTR1AHTR2ASIGMAR1HRH1 | |
| SCHEMBL11834769 | 0.76 | MEN1 (0.50) | HTR1AHTR2ADRD3SIGMAR1DRD1 | |
| SCHEMBL11827651 | 0.75 | HTR1A (0.51) | DRD2HTR1AHTR2ASIGMAR1HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933824-A | Piperazinobutyrophenone derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-01-20 | — | — | US | disclosed |