Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11826952 | 0.87 | HTR1A (0.48) | SIGMAR1HTR1A | |
| SCHEMBL11829630 | 0.82 | SIGMAR1 (0.56) | SIGMAR1HRH3HTR1A | |
| SCHEMBL11822913 | 0.81 | SIGMAR1 (0.47) | SIGMAR1HTR1A | |
| SCHEMBL11825896 | 0.81 | DRD2 (0.46) | SIGMAR1HTR1A | |
| SCHEMBL11830413 | 0.79 | HTR1A (0.64) | HTR1A | |
| SCHEMBL11827651 | 0.79 | HTR1A (0.51) | SIGMAR1HTR1A | |
| SCHEMBL11834202 | 0.77 | DRD2 (0.61) | SIGMAR1HTR1AADRA1A | |
| SCHEMBL11828423 | 0.77 | HTR1A (0.52) | SIGMAR1HTR1A | |
| SCHEMBL11830955 | 0.77 | POLB (0.46) | SIGMAR1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL11823642 | 0.76 | SLC2A1 (0.46) | SIGMAR1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933824-A | Piperazinobutyrophenone derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-01-20 | — | — | US | disclosed |