Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 6/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 6/20 | 0.46 |
| ▸ | TNF | P01375 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | CTSA | P10619 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11826969 | 0.83 | AKR1C3 (0.44) | AKR1C3AKR1C2LMNAFFAR1 | |
| SCHEMBL11836851 | 0.82 | ALOX5 (0.42) | AKR1C3AKR1C2LMNAFFAR1 | |
| SCHEMBL11830155 | 0.81 | PRKAG1 (0.44) | AKR1C3AKR1C2LMNAFFAR1MME | |
| SCHEMBL11836380 | 0.81 | PTGS1 (0.38) | AKR1C3AKR1C2LMNACTSAFFAR1 | |
| SCHEMBL11826110 | 0.80 | HPGD (0.38) | AKR1C3AKR1C2LMNAFFAR1 | |
| SCHEMBL11831306 | 0.80 | AKR1C3 (0.56) | AKR1C3AKR1C2LMNAFFAR1 | |
| SCHEMBL11829192 | 0.80 | HPGD (0.38) | AKR1C3AKR1C2LMNAFFAR1 | |
| SCHEMBL11825726 | 0.80 | ALDH1A1 (0.38) | AKR1C3AKR1C2LMNAFFAR1 | |
| SCHEMBL11829271 | 0.80 | ADAMTS4 (0.38) | AKR1C3AKR1C2LMNAFFAR1 | |
| SCHEMBL11830219 | 0.80 | FFAR1 (0.39) | AKR1C3AKR1C2LMNAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |