SCHEMBL118272

SCHEMBL118272

CC1CCC(C(C)C)C(OC(C)CCO)C1

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.48
TRPM8 Q7Z2W7 3/20 0.44
TRPA1 O75762 2/20 0.44
LMNA P02545 2/20 0.43
EPHX1 P07099 3/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
CYP19A1 P11511 2/20 0.41
KDM4E B2RXH2 1/20 0.41
APOBEC3A P31941 1/20 0.41
APOBEC3G Q9HC16 1/20 0.41
GAA P10253 1/20 0.40
HPGD P15428 1/20 0.39
P2RX4 Q99571 1/20 0.38
NFE2L2 Q16236 1/20 0.38
NTSR1 P30989 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6353121 1.00 ALDH1A1 (0.48) ALDH1A1TRPM8TRPA1LMNAEPHX1
SCHEMBL584338 0.87 ALDH1A1 (0.50) ALDH1A1TRPM8TRPA1LMNAEPHX1
SCHEMBL536505 0.86 ALDH1A1 (0.47) ALDH1A1TRPM8TRPA1LMNAEPHX1
SCHEMBL4581994 0.83 ALDH1A1 (0.44) ALDH1A1TRPM8TRPA1LMNAEPHX1
SCHEMBL18473587 0.83 ALDH1A1 (0.47) ALDH1A1TRPM8TRPA1LMNAEPHX1
SCHEMBL4582679 0.82 ALDH1A1 (0.43) ALDH1A1TRPM8TRPA1LMNAEPHX1
SCHEMBL1701796 0.81 ALDH1A1 (0.51) ALDH1A1TRPM8TRPA1LMNAEPHX1
SCHEMBL22130836 0.81 ALDH1A1 (0.51) ALDH1A1TRPM8TRPA1LMNAEPHX1
SCHEMBL12674222 0.81 ALDH1A1 (0.51) ALDH1A1TRPM8TRPA1LMNAEPHX1
SCHEMBL23187810 0.80 ALDH1A1 (0.50) ALDH1A1TRPM8TRPA1LMNAEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 317 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240041726-A1 FOAMABLE COMPOSITION, USE THEREOF, AND PROCESS FOR ITS PREPARATION CHATTEM, INC. 2024-02-08 US claimed
EP-4231985-A1 FOAMABLE COMPOSITION, USE THEREOF, AND PROCESS FOR ITS PREPARATION Chattem, Inc. (US) 2023-08-30 EP claimed
CN-116322613-A Foamable composition, use thereof and method for the production thereof 查泰姆公司 2023-06-23 CN claimed
WO-2022087343-A1 FOAMABLE COMPOSITION, USE THEREOF, AND PROCESS FOR ITS PREPARATION CHATTEM, INC. (US) 2022-04-28 WO claimed
EP-3169365-A2 COMPOUNDS AND METHODS FOR THE TREATMENT OF ITCH Westfälische Wilhelms-Universität Münster (DE) 2017-05-24 EP claimed
WO-2015169884-A2 COMPOUNDS AND METHODS FOR THE TREATMENT OF ITCH WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER (DE) 2015-11-12 WO claimed
EP-2355665-A1 SENSATE- PLATED SANDING COMPOSITION AND PRODUCTS MADE THEREFROM Kraft Foods Global Brands LLC (US) 2011-08-17 EP claimed
WO-2010056697-A1 SENSATE- PLATED SANDING COMPOSITION AND PRODUCTS MADE THEREFROM CADBURY ADAMS USA LLC (US) 2010-05-20 WO claimed
EP-1215258-B1 Flavor composition for food and drink or for oral care preparation TAKASAGO PERFUMERY CO LTD (JP) 2010-02-17 EP claimed
EP-1215257-B1 Fragance composition TAKASAGO PERFUMERY CO LTD (JP) 2009-10-21 EP claimed
WO-2007126430-A1 COMPOSITIONS PROVIDING A HEATING SENSATION FOR ORAL OR DERMAL DELIVERY CADBURY ADAMS USA LLC (US) 2007-11-08 WO claimed
WO-2007089652-A2 FLAVOR-ENHANCING COMPOSITIONS, METHODS OF MANUFACTURE, AND METHODS OF USE CADBURY ADAMS USA LLC (US) 2007-08-09 WO claimed
WO-2006127738-A9 COMPRESSIBLE CHEWING GUMS FOR DELIVERY OF ACTIVES CADBURY ADAMS USA LLC (US) 2007-05-31 WO claimed
WO-2006127738-A2 COMPRESSIBLE CHEWING GUMS FOR DELIVERY OF ACTIVES CADBURY ADAMS USA LLC (US) 2006-11-30 WO claimed
WO-2006127740-A2 INDICIA-BEARING PACKAGE FOR DELIVERY SYSTEMS FOR MANAGING RELEASE OF SWEETENERS, SENSATES, FUNCTIONAL INGREDIENTS, FOOD ACIDS AND FLAVORS IN A COMPRESSIBLE GUM SYSTEM CADBURY ADAMS USA LLC (US) 2006-11-30 WO claimed
US-6838106-B2 Warming composition for food and drink or for oral care preparation TAKASAGO INTERNATIONAL CORPORATION (JP) 2005-01-04 US claimed
US-6673844-B2 REDUCING SKIN SENSITIVITY TAKASAGO INTERNATIONAL CORPORATION (JP) 2004-01-06 US claimed
US-20020198412-A1 (1R, 2S, 5R)-3-1-menthoxyalkan-1-OL cooling sensate GREEN CARTER B (US) 2002-12-26 US claimed
US-20020142015-A1 Warming composition TAKASAGO INTERNATIONAL CORPORATION 2002-10-03 US claimed
EP-1215257-A2 Warming composition Takasago International Corporation (JP) 2002-06-19 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020142015-A1 Warming composition CUTA, TRPA1, POLR1C ALDH1A1 1699/4885TRPM8 24/4885TRPA1 2/4885
US-20020198412-A1 (1R, 2S, 5R)-3-1-menthoxyalkan-1-OL cooling sensate TAS1R1, TAS2R1, TAS1R3 ALDH1A1 76/4885TRPM8 35/4885TRPA1 26/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.