Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.47 |
| ▸ | RXRB | P28702 | 3/20 | 0.47 |
| ▸ | RXRG | P48443 | 3/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.47 |
| ▸ | P4HB | P07237 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ADH5 | P11766 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL827082 | 0.85 | RXRA (0.48) | RXRARXRBRXRGSRD5A2P4HB | |
| SCHEMBL31319449 | 0.85 | RXRA (0.48) | RXRARXRBRXRGSRD5A2P4HB | |
| SCHEMBL841228 | 0.84 | KIF11 (0.51) | MAPTPDK2AKR1C3AKR1C2 | |
| SCHEMBL7026695 | 0.83 | CES2 (0.50) | RXRARXRBRXRGSRD5A2P4HB | |
| SCHEMBL336261 | 0.83 | ADH5 (0.54) | RXRARXRBRXRGSRD5A2P4HB | |
| Hydrochloric Acid SCHEMBL23302229 | 0.82 | CES2 (0.48) | RXRARXRBRXRGSRD5A2P4HB | |
| SCHEMBL78878 | 0.82 | TAS1R3 (0.54) | RXRARXRBRXRGSRD5A2P4HB | |
| SCHEMBL402677 | 0.82 | P4HB (0.62) | RXRARXRBRXRGSRD5A2P4HB | |
| Hydrochloric Acid SCHEMBL9229512 | 0.82 | ADH5 (0.52) | RXRARXRBRXRGSRD5A2P4HB | |
| SCHEMBL321273 | 0.82 | MAPT (0.55) | RXRARXRBRXRGSRD5A2P4HB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |