Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 2/20 | 0.43 |
| ▸ | CTSA | P10619 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11843420 | 0.86 | DHFR (0.43) | DHFRCTSARXRARXRB | |
| SCHEMBL11841366 | 0.86 | PPARG (0.44) | RXRARXRBPPARGPPARA | |
| SCHEMBL11833412 | 0.85 | CYP1A2 (0.45) | RXRARXRB | |
| SCHEMBL11833666 | 0.85 | HNF4A (0.43) | DHFRRXRARXRBLMNAEGFR | |
| SCHEMBL11839394 | 0.84 | DHFR (0.44) | DHFRCTSANR1H4PPARGPPARA | |
| SCHEMBL11838131 | 0.84 | CYP1A2 (0.42) | RXRARXRBMAPT | |
| SCHEMBL11839024 | 0.84 | FFAR1 (0.50) | RXRARXRB | |
| SCHEMBL11839906 | 0.84 | ALDH1A1 (0.44) | RXRARXRBLMNAMAPT | |
| SCHEMBL11848998 | 0.84 | RXRA (0.41) | RXRARXRBPPARGPPARAMAPT | |
| SCHEMBL11831566 | 0.84 | THRB (0.41) | RXRARXRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3941821-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETICS | WILLIAM H. RORER, INC. (US) | 1976-03-02 | — | — | US | disclosed |