Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11841366 | 0.86 | PPARG (0.44) | MEN1KMT2ARAB9ANPC1RXRA | |
| SCHEMBL11833666 | 0.85 | HNF4A (0.43) | ALDH1A1MEN1KMT2AHPGDRAB9A | |
| SCHEMBL11833412 | 0.85 | CYP1A2 (0.45) | MEN1KMT2ARAB9ANPC1RXRA | |
| SCHEMBL11846286 | 0.85 | ALDH1A1 (0.45) | ALDH1A1HSD17B10MEN1KMT2AMAPT | |
| SCHEMBL11839024 | 0.84 | FFAR1 (0.50) | MEN1KMT2AHPGDRAB9ANPC1 | |
| SCHEMBL11831566 | 0.84 | THRB (0.41) | MEN1KMT2ARAB9ANPC1GAA | |
| SCHEMBL11836749 | 0.84 | DHFR (0.43) | MAPTRXRARXRBLMNA | |
| SCHEMBL11848998 | 0.84 | RXRA (0.41) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL11838131 | 0.84 | CYP1A2 (0.42) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL11845888 | 0.82 | RXRA (0.42) | ALDH1A1MEN1KMT2AMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3941821-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETICS | WILLIAM H. RORER, INC. (US) | 1976-03-02 | — | — | US | disclosed |