Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 4/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11684159 | 0.90 | SIGMAR1 (0.44) | SIGMAR1HTR2CSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11853705 | 0.85 | SIGMAR1 (0.49) | SIGMAR1OPRD1KCNH2KDM1AMAOA | |
| SCHEMBL11782410 | 0.81 | DRD1 (0.44) | SIGMAR1HTR2AOPRD1KCNH2 | |
| SCHEMBL11682880 | 0.81 | OPRD1 (0.41) | SIGMAR1SLC6A2SLC6A4SLC6A3OPRD1 | |
| SCHEMBL29705809 | 0.80 | OPRD1 (0.50) | SIGMAR1OPRD1KCNH2 | |
| SCHEMBL4363631 | 0.80 | OPRD1 (0.50) | SIGMAR1OPRD1KCNH2 | |
| SCHEMBL11853721 | 0.78 | PRCP (0.42) | SIGMAR1SLC6A2SLC6A4SLC6A3OPRD1 | |
| SCHEMBL11883509 | 0.78 | PRCP (0.48) | — | |
| SCHEMBL11739762 | 0.78 | SIGMAR1 (0.37) | SIGMAR1HTR2CSLC6A2SLC6A3HTR2A | |
| SCHEMBL11680301 | 0.74 | OPRD1 (0.43) | SIGMAR1SLC6A2SLC6A4SLC6A3OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3996354-A | 1,3-Dihydro-1'-dimethylphosphinylalkyl-3-phenylspiro(isobenzofuran)s | AMERICAN HOECHST CORPORATION (US) | 1976-12-07 | — | — | US | disclosed |