Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | LDHB | P07195 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11843290 | 0.81 | ABCC4 (0.54) | LMNATSHR | |
| SCHEMBL11837625 | 0.80 | CYP4F2 (0.44) | L3MBTL1SMN1; SMN2NPC1PKMNFKB1 | |
| SCHEMBL11839428 | 0.80 | MAPT (0.49) | L3MBTL1SMN1; SMN2NPC1PKMNFKB1 | |
| SCHEMBL11832497 | 0.80 | LMNA (0.47) | L3MBTL1SMN1; SMN2NPC1PKMNFKB1 | |
| SCHEMBL11839196 | 0.79 | ALDH1A1 (0.48) | L3MBTL1SMN1; SMN2NPC1PKMNFKB1 | |
| SCHEMBL11727313 | 0.77 | CA12 (0.47) | L3MBTL1SMN1; SMN2NPC1PKMNFKB1 | |
| SCHEMBL3227634 | 0.76 | GAA (0.58) | L3MBTL1SMN1; SMN2NPC1PKMNFKB1 | |
| SCHEMBL68930 | 0.75 | CYP4Z1 (0.57) | L3MBTL1SMN1; SMN2NPC1PKMNFKB1 | |
| SCHEMBL11847298 | 0.74 | MAPT (0.51) | L3MBTL1SMN1; SMN2NPC1PKMNFKB1 | |
| Hydrochloric Acid SCHEMBL7390203 | 0.74 | L3MBTL1 (0.56) | L3MBTL1SMN1; SMN2NPC1PKMNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3941821-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETICS | WILLIAM H. RORER, INC. (US) | 1976-03-02 | — | — | US | disclosed |