Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11837625 | 0.82 | CYP4F2 (0.44) | ALDH1A1L3MBTL1THRBHPGDMAPT | |
| SCHEMBL11839428 | 0.82 | MAPT (0.49) | ALDH1A1L3MBTL1THRBHPGDMAPT | |
| SCHEMBL11849679 | 0.81 | LMNA (0.56) | ALDH1A1L3MBTL1RXRARXRBRXRG | |
| SCHEMBL11837941 | 0.80 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1THRBHPGDLMNA | |
| SCHEMBL11844403 | 0.79 | L3MBTL1 (0.43) | ALDH1A1L3MBTL1THRBHPGDLMNA | |
| SCHEMBL11727313 | 0.79 | CA12 (0.47) | ALDH1A1L3MBTL1THRBHPGDMAPT | |
| SCHEMBL3227634 | 0.78 | GAA (0.58) | ALDH1A1L3MBTL1THRBLMNAHTT | |
| SCHEMBL68930 | 0.77 | CYP4Z1 (0.57) | ALDH1A1L3MBTL1THRBLMNAMAPT | |
| Hydrochloric Acid SCHEMBL7390203 | 0.76 | L3MBTL1 (0.56) | ALDH1A1L3MBTL1THRBLMNAHTT | |
| SCHEMBL11847298 | 0.76 | MAPT (0.51) | ALDH1A1L3MBTL1THRBLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3941821-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETICS | WILLIAM H. RORER, INC. (US) | 1976-03-02 | — | — | US | disclosed |