Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HCAR3 | P49019 | 7/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11839922 | 0.88 | MAPT (0.75) | MAPTGAAHCAR3ALDH1A1MEN1 | |
| SCHEMBL11848393 | 0.83 | CA2 (0.43) | MAPTGAASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL11846149 | 0.82 | HCAR3 (0.58) | MAPTGAAHCAR3ALDH1A1MEN1 | |
| SCHEMBL11847155 | 0.79 | KMT2A (0.55) | MAPTGAASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL11851335 | 0.76 | ALDH1A1 (0.58) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL11842797 | 0.76 | HCAR3 (0.53) | MAPTGAAHCAR3ALDH1A1MEN1 | |
| SCHEMBL7570478 | 0.72 | MAPT (0.92) | MAPTGAAHCAR3ALDH1A1MEN1 | |
| SCHEMBL2883308 | 0.72 | HCAR3 (0.55) | MAPTSMN1; SMN2HCAR3ALDH1A1MEN1 | |
| SCHEMBL11849602 | 0.72 | MAPT (0.51) | MAPTGAASMN1; SMN2HCAR3ALDH1A1 | |
| SCHEMBL11843965 | 0.72 | MAPT (0.51) | MAPTGAASMN1; SMN2HCAR3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3985777-A | Sulphamyl-benzoic acid derivatives | LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB (DK) | 1976-10-12 | — | — | US | disclosed |