Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | ACLY | P53396 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11847444 | 0.84 | ALDH1A1 (0.47) | LMNATSHRKDM4EUSP2ALDH1A1 | |
| SCHEMBL11846360 | 0.84 | PKM (0.60) | LMNATSHRKDM4EUSP2ALDH1A1 | |
| SCHEMBL11842089 | 0.83 | LMNA (0.51) | LMNATSHRKDM4EUSP2ALDH1A1 | |
| SCHEMBL11849419 | 0.82 | ALDH1A1 (0.49) | LMNATSHRKDM4EUSP2ALDH1A1 | |
| SCHEMBL30241206 | 0.80 | ALDH1A1 (0.50) | LMNATSHRKDM4EUSP2ALDH1A1 | |
| SCHEMBL28945970 | 0.80 | ALDH1A1 (0.50) | LMNATSHRKDM4EUSP2ALDH1A1 | |
| SCHEMBL11838980 | 0.79 | ALDH1A1 (0.47) | LMNATSHRKDM4EUSP2ALDH1A1 | |
| SCHEMBL11799270 | 0.78 | CA1 (0.43) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11780330 | 0.78 | MEN1 (0.47) | LMNATSHRCA2PKMSMN1; SMN2 | |
| SCHEMBL574020 | 0.76 | HSD17B10 (0.64) | LMNATSHRKDM4EUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3939267-A | DIURETIC | CIBA-GEIGY CORPORATION (US) | 1976-02-17 | — | — | US | disclosed |