Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11846815 | 0.86 | THRB (0.44) | PKML3MBTL1POLBLMNAMEN1 | |
| SCHEMBL11844827 | 0.84 | LMNA (0.45) | PKMPOLBLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL11780362 | 0.84 | PKM (0.65) | PKML3MBTL1POLBLMNASMN1; SMN2 | |
| SCHEMBL11846152 | 0.83 | HPSE (0.46) | POLBLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30241210 | 0.81 | ALDH1A1 (0.44) | POLBLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28945995 | 0.81 | ALDH1A1 (0.44) | POLBLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11799395 | 0.80 | LMNA (0.59) | PKML3MBTL1POLBLMNAMEN1 | |
| SCHEMBL14879785 | 0.80 | VCAM1 (0.51) | PKMPOLBLMNAMEN1KMT2A | |
| SCHEMBL11780616 | 0.80 | PKM (0.59) | PKML3MBTL1POLBLMNAMEN1 | |
| SCHEMBL11842089 | 0.80 | LMNA (0.51) | PKML3MBTL1POLBLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3939267-A | DIURETIC | CIBA-GEIGY CORPORATION (US) | 1976-02-17 | — | — | US | disclosed |