Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 9/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13964061 | 0.76 | RAB9A (0.58) | TGFBR1RAB9A | |
| SCHEMBL11846894 | 0.74 | TUBB4A (0.49) | RAB9ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL16097590 | 0.72 | ALDH1A1 (0.55) | TGFBR1RAB9AIRAK4 | |
| SCHEMBL11851657 | 0.70 | KDM4E (0.50) | RAB9AFAAHMGLL | |
| SCHEMBL11846190 | 0.69 | ALDH1A1 (0.44) | RAB9ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL13596807 | 0.68 | PDE4B (0.47) | RAB9A | |
| SCHEMBL8256698 | 0.68 | SLC9A1 (0.50) | RAB9ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL31289323 | 0.68 | SLC9A1 (0.50) | RAB9ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL12435278 | 0.67 | HTR3E (0.43) | TGFBR1IRAK4HTR3EHTR3BHTR3A | |
| SCHEMBL11553878 | 0.67 | GABRP (0.50) | RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4000286-A | ANALGESICS, ANTIINFLAMMATORY AND ANTIPYRETIC AGENTS | MERCK & CO., INC. (US) | 1976-12-28 | — | — | US | disclosed |