Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NMT1 | P30419 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30753697 | 0.82 | ALDH1A1 (0.50) | MAPTALDH1A1L3MBTL1HPGDACHE | |
| SCHEMBL11098419 | 0.82 | ACHE (0.38) | LMNAMAPTALDH1A1L3MBTL1HPGD | |
| SCHEMBL5168941 | 0.79 | ACHE (0.46) | LMNAMAPTALDH1A1ACHEKMT2A | |
| SCHEMBL8168991 | 0.79 | MAOA (0.47) | LMNAMAPTALDH1A1L3MBTL1NCOA3 | |
| SCHEMBL25034012 | 0.78 | MTNR1A (0.54) | LMNAALDH1A1L3MBTL1HPGDALOX15 | |
| SCHEMBL17277336 | 0.77 | KIF11 (0.49) | MAPTALDH1A1L3MBTL1TDP1ACHE | |
| SCHEMBL10144174 | 0.77 | ACHE (0.44) | ALDH1A1L3MBTL1HPGDACHEKMT2A | |
| SCHEMBL15856977 | 0.77 | NPC1 (0.47) | MAPTALDH1A1ESR1HPGDALOX15 | |
| SCHEMBL6402484 | 0.77 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1KMT2AMAPK1HTT | |
| SCHEMBL4184128 | 0.76 | ACHE (0.42) | MAPTALDH1A1L3MBTL1HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3984336-A | BETA-THIO-PROPIONITRILE, ANTIWEAR AGENTS | MOBIL OIL CORPORATION (US) | 1976-10-05 | — | — | US | disclosed |