Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | PKM | P14618 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | BLM | P54132 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11860933 | 0.85 | ADORA3 (0.46) | ADORA2AALDH1A1LMNATSHRADORA2B | |
| SCHEMBL11870272 | 0.82 | ALDH1A1 (0.46) | CASRADORA2AALDH1A1PKMTSHR | |
| SCHEMBL11868954 | 0.81 | CHEK1 (0.43) | ADORA2ALMNAADORA2BADORA1MAPT | |
| SCHEMBL11162361 | 0.80 | LMNA (0.54) | LMNAMAPTPOLBTP53 | |
| SCHEMBL11867581 | 0.79 | ADORA2A (0.43) | CASRADORA2AALDH1A1LMNAPKM | |
| SCHEMBL11468014 | 0.76 | LMNA (0.56) | LMNAMAPTPOLBTP53 | |
| SCHEMBL11867768 | 0.75 | MAPT (0.40) | ADORA2AALDH1A1LMNATSHRSMN1; SMN2 | |
| SCHEMBL14347514 | 0.72 | RORA (0.40) | ALDH1A1LMNATSHRKDM4EMAPT | |
| SCHEMBL14374207 | 0.72 | MAT2A (0.43) | ALDH1A1LMNATSHRKDM4EMAPT | |
| SCHEMBL11462895 | 0.68 | MAPT (0.44) | LMNAMAPTPOLBTDP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3950526-A | Quinazoline derivatives in pharmaceutical compositions for treating pain and inflammation | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-04-13 | — | — | US | disclosed |