Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.34 |
| ▸ | HTR3B | O95264 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.34 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.31 |
| ▸ | ORAI2 | Q96SN7 | 2/20 | 0.31 |
| ▸ | ORAI3 | Q9BRQ5 | 2/20 | 0.31 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29404220 | 0.75 | TSHR (0.47) | TSHRLMNAALDH1A1CES2CES1 | |
| SCHEMBL4129 | 0.75 | TSHR (0.47) | TSHRLMNAALDH1A1CES2CES1 | |
| SCHEMBL28117905 | 0.73 | TSHR (0.45) | TSHRLMNAALDH1A1CES2CES1 | |
| Benzene SCHEMBL28042388 | 0.73 | LMNA (0.45) | TSHRLMNAALDH1A1CES2CES1 | |
| SCHEMBL14217841 | 0.71 | TSHR (0.43) | TSHRLMNAALDH1A1CES2CES1 | |
| 1,2-Dichlorobenzene SCHEMBL28043924 | 0.68 | TSHR (0.71) | TSHRLMNAALDH1A1HTR3EHTR3B | |
| SCHEMBL16104430 | 0.68 | ENPP2 (0.45) | TSHRLMNAALDH1A1CES2CES1 | |
| SCHEMBL31125058 | 0.67 | ENPP2 (0.39) | TSHRLMNAALDH1A1ADRB1ORAI1 | |
| SCHEMBL27933411 | 0.67 | TSHR (0.38) | TSHRLMNAALDH1A1CES2CES1 | |
| SCHEMBL4833079 | 0.67 | ALDH1A1 (0.41) | TSHRLMNAALDH1A1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7888356-B2 | Antibiotics containing borinic acid complexes and methods of use | ANACOR PHARMACEUTICALS, INC. (US) | 2011-02-15 | — | — | US | disclosed |
| CN-101928295-A | Antibiotics containing borinic acid complexes and methods of use | ANACOR PHARMACEUTICALS INC | 2010-12-29 | — | — | CN | disclosed |
| EP-2044091-A2 | COMPOUNDS FOR THE TREATMENT OF PERIODONTAL DISEASE | Anacor Pharmaceuticals, Inc. (US) | 2009-04-08 | — | — | EP | disclosed |
| US-20080293675-A1 | ANTIBIOTICS CONTAINING BORINIC ACID COMPLEXES AND METHODS OF USE | ANACOR PHARMACEUTCALS INC. (US) | 2008-11-27 | — | — | US | disclosed |
| EP-1980564-A1 | Antibiotics containing borinic acid complexes and methods of use | Anacor Pharmaceuticals, Inc. (US) | 2008-10-15 | — | — | EP | disclosed |
| US-7393856-B2 | Anti-viral uses of borinic acid complexes | ANACOR PHARMACEUTICALS, INC. (US) | 2008-07-01 | — | — | US | disclosed |
| US-7390806-B2 | Antibiotics containing borinic acid complexes and methods of use | ANACOR PHARMACEUTICALS, INC. (US) | 2008-06-24 | — | — | US | disclosed |
| US-20080146803-A1 | ANTIBIOTICS CONTAINING BORINIC ACID COMPLEXES AND METHODS OF USE | ANACOR PHARMACEUTICALS, INC. | 2008-06-19 | — | — | US | disclosed |
| EP-1581500-A4 | ANTIBIOTICS CONTAINING BORINIC ACID COMPLEXES AND METHODS OF USE | ANACOR PHARMACEUTICALS INC (US) | 2008-03-05 | — | — | EP | disclosed |
| WO-2007146965-A2 | COMPOUNDS FOR THE TREATMENT OF PERIODONTAL DISEASE | ANACOR PHARMACEUTICALS, INC. (US) | 2007-12-21 | — | — | WO | disclosed |
| WO-2006085932-A2 | ANTI-VIRAL USES OF BORINIC ACID COMPLEXES | ANACOR PHARMACEUTICALS, INC. (US) | 2006-08-17 | — | — | WO | disclosed |
| CN-1738802-A | Antibiotics containing boronic acid complexes and methods of use | ANACOR PHARMACEUTICALS INC (US) | 2006-02-22 | — | — | CN | disclosed |
| US-20060019927-A1 | Anti-viral uses of borinic acid complexes | ANACOR PHARMACEUTICALS, INC. | 2006-01-26 | — | — | US | disclosed |
| WO-2006007384-A2 | ANTIBIOTICS CONTAINING BORINIC ACID COMPLEXES AND METHODS OF USE | ANACOR PHARMACEUTICALS, INC. (US) | 2006-01-19 | — | — | WO | disclosed |
| US-20060014723-A1 | Anti-parasitic uses of borinic acid complexes | ANACOR PHARMACEUTICALS, INC. | 2006-01-19 | — | — | US | disclosed |
| WO-2005123095-A1 | ANTI-PARASITIC USES OF BORINIC ACID COMPLEXES | ANACOR PHARMACEUTICALS, INC. (US) | 2005-12-29 | — | — | WO | disclosed |
| EP-1581500-A2 | ANTIBIOTICS CONTAINING BORINIC ACID COMPLEXES AND METHODS OF USE | Anacor Pharmaceuticals, Inc. (US) | 2005-10-05 | — | — | EP | disclosed |
| US-20050070503-A1 | Antibiotics containing borinic acid complexes and methods of use | ANACOR PHARMACEUTICALS, INC. | 2005-03-31 | — | — | US | disclosed |
| US-20040224923-A1 | Antibiotics containing borinic acid complexes and methods of use | ANACOR PHARMACEUTICALS, INC. | 2004-11-11 | — | — | US | disclosed |
| WO-2004056322-A2 | ANTIBIOTICS CONTAINING BORINIC ACID COMPLEXES AND METHODS OF USE | ANACOR PHARMACEUTICALS, INC. (US) | 2004-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040224923-A1 | Antibiotics containing borinic acid complexes and methods of use | BPGM, BROX, TBCA | TSHR 3038/4885LMNA 594/4885ALDH1A1 4215/4885 |
| US-20060014723-A1 | Anti-parasitic uses of borinic acid complexes | BPGM, HRH1, HRH3 | TSHR 3633/4885LMNA 928/4885ALDH1A1 2879/4885 |
| US-20080146803-A1 | ANTIBIOTICS CONTAINING BORINIC ACID COMPLEXES AND METHODS OF USE | BPGM, BROX, TBCA | TSHR 3038/4885LMNA 594/4885ALDH1A1 4215/4885 |
| US-20050070503-A1 | Antibiotics containing borinic acid complexes and methods of use | BPGM, BROX, TBCA | TSHR 3038/4885LMNA 594/4885ALDH1A1 4215/4885 |
| US-20060019927-A1 | Anti-viral uses of borinic acid complexes | SSB, BPGM, HAVCR2 | TSHR 4453/4885LMNA 1188/4885ALDH1A1 3836/4885 |
| US-20080293675-A1 | ANTIBIOTICS CONTAINING BORINIC ACID COMPLEXES AND METHODS OF USE | BPGM, BROX, TBCA | TSHR 3038/4885LMNA 594/4885ALDH1A1 4215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.