Benzenesulfonamide

Benzenesulfonamide

SCHEMBL11870525

CN(C)c1ccc(Cc2ccc(N(C)C)cc2)cc1.NS(=O)(=O)c1ccccc1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 17/20 0.60
CA1 P00915 13/20 0.60
CA9 Q16790 12/20 0.60
CA12 O43570 11/20 0.60
CA14 Q9ULX7 4/20 0.60
CA7 P43166 2/20 0.59
ALDH1A1 P00352 2/20 0.57
CYP3A4 P08684 1/20 0.57
TSHR P16473 1/20 0.57
MAPK1 P28482 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
CA4 P22748 2/20 0.55
MEN1 O00255 1/20 0.54
NPC1 O15118 1/20 0.54
POLB P06746 1/20 0.54
RAB9A P51151 1/20 0.54
KMT2A Q03164 1/20 0.54
CA3 P07451 1/20 0.53
CA6 P23280 1/20 0.53
CA5A P35218 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10690610 0.80 CA2 (0.89) CA2CA1CA9CA12CA14
Diphenylmethane SCHEMBL15033700 0.80 ALDH1A1 (0.81) ALDH1A1CYP3A4TSHRMAPK1TDP1
SCHEMBL330045 0.80 CA2 (0.78) CA2CA1CA9CA12CA14
SCHEMBL5580184 0.80 ALDH1A1 (0.81) ALDH1A1CYP3A4TSHRMAPK1TDP1
Hydrochloric Acid SCHEMBL8030257 0.78 ALDH1A1 (0.77) ALDH1A1CYP3A4TSHRMAPK1TDP1
Benzenesulfonamide SCHEMBL9749590 0.77 CA2 (0.50) CA2CA1CA9CA12CA14
Benzenesulfonamide SCHEMBL9750114 0.76 CA2 (0.49) CA2CA1CA9CA12CA14
SCHEMBL309694 0.75 CA2 (0.73) CA2CA1CA9CA12CA14
SCHEMBL76217 0.75 ALDH1A1 (1.00) ALDH1A1CYP3A4TSHRMAPK1TDP1
SCHEMBL12679051 0.75 ALDH1A1 (1.00) ALDH1A1CYP3A4TSHRMAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3936361-A ELECTROCONDUCTIVITY TAKATORI YASUSHI 1976-02-03 US disclosed