Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9849973 | 0.76 | TSHR (0.49) | KCNMA1 | |
| SCHEMBL7829392 | 0.69 | ALDH1A1 (0.31) | — | |
| SCHEMBL7417577 | 0.67 | CYP19A1 (0.47) | — | |
| SCHEMBL25522978 | 0.67 | TSHR (0.33) | — | |
| SCHEMBL18274469 | 0.67 | — | — | |
| SCHEMBL1275688 | 0.67 | TRPA1 (0.46) | — | |
| SCHEMBL3447644 | 0.67 | TRPA1 (0.46) | — | |
| SCHEMBL11814736 | 0.63 | HTT (0.39) | — | |
| SCHEMBL18762857 | 0.63 | — | — | |
| SCHEMBL9850045 | 0.63 | ALOX5 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933811-A | N-aminomethyl-2-amino(and 2-amino-methyl)-2-(2-quinolyl)-thioacetamides | SMITHKLINE CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |