Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | FADS1 | O60427 | 1/20 | 0.56 |
| ▸ | NOS2 | P35228 | 2/20 | 0.55 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | GCK | P35557 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29758053 | 0.83 | ABL1 (0.65) | RECQLFADS1NOS2ABL1ALDH1A1 | |
| SCHEMBL400044 | 0.83 | ABL1 (0.65) | RECQLFADS1NOS2ABL1ALDH1A1 | |
| SCHEMBL9540049 | 0.83 | RECQL (0.79) | RECQLFADS1NOS2ABL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7423119 | 0.82 | ABL1 (0.62) | RECQLFADS1NOS2ABL1ALDH1A1 | |
| SCHEMBL620233 | 0.81 | RECQL (0.59) | RECQLFADS1NOS2ABL1ALDH1A1 | |
| SCHEMBL15134168 | 0.81 | RECQL (0.59) | RECQLFADS1NOS2ABL1ALDH1A1 | |
| SCHEMBL31542015 | 0.81 | ALDH1A1 (0.63) | RECQLFADS1NOS2ALDH1A1CYP3A4 | |
| SCHEMBL15503392 | 0.81 | RECQL (0.59) | RECQLFADS1NOS2ABL1ALDH1A1 | |
| SCHEMBL220073 | 0.81 | ALDH1A1 (0.63) | RECQLFADS1NOS2ALDH1A1CYP3A4 | |
| SCHEMBL3880067 | 0.81 | PGR (0.55) | RECQLFADS1ALDH1A1SMN1; SMN2GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149628-A1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF NICOTINAMIDE N-METHYL TRANSFERASE | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | disclosed |
| US-20250145601-A1 | NOVEL BICYCLIC COMPOUNDS AS RAD51 INHIBITORS | SATYA THERAPEUTICS, INC. | 2025-05-08 | — | — | US | disclosed |
| CN-115947690-B | Preparation method of indazole molecular building block and application of indazole molecular building block in drug synthesis | 安徽医科大学 | 2025-04-08 | — | — | CN | disclosed |
| US-20250092065-A1 | 2-(INDAZOL-5-YL)-6-(PIPERIDIN-4-YL)-1,7-NAPHTHYRIDINE DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS FOR SPLICING NUCLEIC ACIDS AND FOR THE TREATMENT OF PROLIFERATIVE DISEASES | REMIX THERAPEUTICS INC (US) | 2025-03-20 | — | — | US | disclosed |
| CN-109790114-B | Novel chiral ligand, metal chelate, various unnatural amino acids and synthesis method of maraviroc and key intermediate thereof | 中国科学院上海药物研究所 | 2025-03-07 | — | — | CN | disclosed |
| US-20250026769-A1 | PAPD5 INHIBITORS AND METHODS OF USE THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2025-01-23 | — | — | US | disclosed |
| CN-118696034-A | Novel bicyclic compounds as RAD51 inhibitors | 萨提亚疗法股份有限公司 | 2024-09-24 | — | — | CN | disclosed |
| CN-116514712-B | Synthesis method of 3-benzyl-2-phenyl-4-quinolone compound | 延安大学 | 2024-09-06 | — | — | CN | disclosed |
| CN-116514712-A | Synthesis method of 3-benzyl-2-phenyl-4-quinolone compound | 延安大学 | 2023-08-01 | — | — | CN | disclosed |
| WO-2023133217-A1 | 2-(INDAZOL-5-YL)-6-(PIPERIDIN-4-YL)-1,7-NAPHTHYRIDINE DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS FOR SPLICING NUCLEIC ACIDS AND FOR THE TREATMENT OF PROLIFERATIVE DISEASES | REMIX THERAPEUTICS INC. (US) | 2023-07-13 | — | — | WO | disclosed |
| US-4656267-A | RENAL VASODILATORS, CARDIOVASCULAR AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1987-04-07 | — | — | US | disclosed |
| US-4647560-A | COGNITION ACTIVATORS | TROPONWERKE GMBH & CO. KG (DE) | 1987-03-03 | — | — | US | disclosed |
| US-4622065-A | HERBICIDES | PPG INDUSTRIES, INC. (US) | 1986-11-11 | — | — | US | disclosed |
| US-4555571-A | Substituted 2(1H)-quinazolinone-1-alkanoic acids and esters | ORTHO PHARMACEUTICAL CORPORATION (US) | 1985-11-26 | — | — | US | disclosed |
| EP-0138491-A2 | Substituted 2(1H)-quinazolinone-1-alkanoic acids and esters | ORTHO PHARMACEUTICAL CORPORATION (US) | 1985-04-24 | — | — | EP | disclosed |
| EP-0048998-B1 | ISONICOTINANILIDE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND PLANT GROWTH REGULATOR CONTAINING THE SAME | Chugai Seiyaku Kabushiki Kaisha (JP) | 1985-01-09 | — | — | EP | disclosed |
| US-4377407-A | Isonicotinanilide derivatives, plant growth regulating compositions and use | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1983-03-22 | — | — | US | disclosed |
| EP-0048998-A2 | Isonicotinanilide derivatives, process for preparing the same and plant growth regulator containing the same | Chugai Seiyaku Kabushiki Kaisha (JP) | 1982-04-07 | — | — | EP | disclosed |
| US-3987047-A | ANORETICS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-10-19 | — | — | US | disclosed |
| US-3950526-A | Quinazoline derivatives in pharmaceutical compositions for treating pain and inflammation | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250092065-A1 | 2-(INDAZOL-5-YL)-6-(PIPERIDIN-4-YL)-1,7-NAPHTHYRIDINE DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS FOR SPLICING NUCLEIC ACIDS AND FOR THE TREATMENT OF PROLIFERATIVE DISEASES | SNRPA, SNRPB2, HNRNPAB | RECQL 682/4885FADS1 3464/4885NOS2 2353/4885 |
| US-20250145601-A1 | NOVEL BICYCLIC COMPOUNDS AS RAD51 INHIBITORS | RAD51, ERCC4, ERCC2 | RECQL 46/4885FADS1 3250/4885NOS2 4331/4885 |
| US-20250026769-A1 | PAPD5 INHIBITORS AND METHODS OF USE THEREOF | POT1, PARP15, TERT | RECQL 728/4885FADS1 3440/4885NOS2 3528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.