Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1189319 | 0.85 | NPSR1 (0.51) | NPSR1GPR55CYP2D6OPRM1CHRM2 | |
| SCHEMBL26094127 | 0.81 | MEN1 (0.62) | ALDH1A1NPSR1GPR55CYP2D6OPRM1 | |
| SCHEMBL3887165 | 0.78 | ALDH1A1 (0.46) | ALDH1A1NPSR1GPR55CYP2D6OPRM1 | |
| SCHEMBL5532770 | 0.78 | ALDH1A1 (0.46) | ALDH1A1NPSR1GPR55CYP2D6OPRM1 | |
| SCHEMBL15409040 | 0.78 | OPRM1 (0.56) | ALDH1A1CYP2D6OPRM1CHRM2CHRM4 | |
| SCHEMBL5502867 | 0.77 | OPRM1 (0.45) | ALDH1A1NPSR1GPR55CYP2D6OPRM1 | |
| SCHEMBL2793637 | 0.77 | ALDH1A1 (0.67) | ALDH1A1CYP2D6OPRM1CHRM2CHRM4 | |
| SCHEMBL10047375 | 0.74 | NPSR1 (0.61) | NPSR1GPR55CYP2D6OPRM1CHRM2 | |
| SCHEMBL3892551 | 0.72 | ALDH1A1 (0.49) | ALDH1A1CYP2D6CYP3A4CYP2C9KDM4E | |
| SCHEMBL31282961 | 0.72 | CYP3A4 (0.53) | ALDH1A1CYP2D6CYP3A4ALOX15CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025111582-A1 | AZA-TETRACYCLIC OXAZEPINE INHIBITORS OF KRAS-G12D | GENENTECH, INC. (US) | 2025-05-30 | — | — | WO | disclosed |
| EP-4547656-A1 | INDAZOLE COMPOUNDS | Tyra Biosciences, Inc. (US) | 2025-05-07 | — | — | EP | disclosed |
| CN-119731165-A | Indazole compounds | 泰拉生物科学公司 | 2025-03-28 | — | — | CN | disclosed |
| WO-2024006897-A1 | INDAZOLE COMPOUNDS | TYRA BIOSCIENCES, INC. (US) | 2024-01-04 | — | — | WO | disclosed |
| WO-2021064077-A1 | SUBSTITUTED PYRAZOLOPYRIMIDINES AS IRAK4 INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2021-04-08 | — | — | WO | disclosed |
| EP-3800188-A1 | SUBSTITUTED PYRAZOLOPYRIMIDINES AS IRAK4 INHIBITORS | Bayer AG (DE) | 2021-04-07 | — | — | EP | disclosed |
| EP-3800188-A1 | SUBSTITUTED PYRAZOLOPYRIMIDINES AS IRAK4 INHIBITORS | Bayer AG (DE) | 2021-04-07 | — | — | EP | disclosed |
| EP-2217226-B1 | PEPTIDE DEFORMYLASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2015-07-22 | — | — | EP | disclosed |
| US-20130045962-A1 | PEPTIDE DEFORMYLASE INHIBITORS | GLAXOSMITHKLINE LLC | 2013-02-21 | — | — | US | disclosed |
| CN-101917981-B | Peptide deformylase inhibitors | SMITHKLINE BEECHAM CORP | 2012-11-14 | — | — | CN | disclosed |
| US-7893056-B2 | Peptide deformylase inhibitors | GLAXOSMITHKLINE LLC (US) | 2011-02-22 | — | — | US | disclosed |
| CN-101917981-A | Peptide deformylase inhibitors | SMITHKLINE BEECHAM CORP | 2010-12-15 | — | — | CN | disclosed |
| EP-2217226-A1 | PEPTIDE DEFORMYLASE INHIBITORS | GlaxoSmithKline LLC (US) | 2010-08-18 | — | — | EP | disclosed |
| US-20090306066-A1 | PEPTIDE DEFORMYLASE INHIBITORS | GLAXOSMITHKLINE LLC | 2009-12-10 | — | — | US | disclosed |
| WO-2009061879-A1 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130045962-A1 | PEPTIDE DEFORMYLASE INHIBITORS | PDF, DPEP1, DHPS | ALDH1A1 985/4885NPSR1 1670/4885GPR55 3338/4885 |
| US-20090306066-A1 | PEPTIDE DEFORMYLASE INHIBITORS | PDF, DHPS, PADI3 | ALDH1A1 1567/4885NPSR1 2601/4885GPR55 3424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.