SCHEMBL11902404

SCHEMBL11902404

CCOC(C)OC(=O)c1nc(-c2ccc(Cl)c(OC)c2F)nc2[nH]cc(C)c12

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.32
▸ MEP1B Q16820 1/20 0.31
▸ JAK2 O60674 1/20 0.31
▸ JAK3 P52333 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11903414 0.92 SMN1; SMN2 (0.36) L3MBTL1
SCHEMBL11903412 0.90 L3MBTL1 (0.31) L3MBTL1MEP1BJAK2JAK3
SCHEMBL11902200 0.89 MEP1B (0.34) MEP1B
SCHEMBL11903334 0.88 JAK3 (0.38) MEP1BJAK2JAK3
SCHEMBL1654718 0.86 TAS1R3 (0.34) MEP1B
SCHEMBL11903242 0.86 ALDH1A1 (0.33) L3MBTL1
SCHEMBL11902294 0.85 PTGES (0.33) MEP1B
SCHEMBL11902938 0.85 SMN1; SMN2 (0.31) MEP1B
SCHEMBL11903416 0.84 SMN1; SMN2 (0.32) JAK2JAK3
SCHEMBL11903327 0.84 SMN1; SMN2 (0.33) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120202690-A1 HERBICIDAL COMPOUNDS SYNGENTA LIMITED (US) 2012-08-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120202690-A1 HERBICIDAL COMPOUNDS DDT, HAO2, HAAO L3MBTL1 2005/4885MEP1B 2906/4885JAK2 3622/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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