Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | TP53 | P04637 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | RUNX1 | Q01196 | 6/20 | 0.59 |
| ▸ | CBFB | Q13951 | 3/20 | 0.59 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11903459 | 0.90 | KDM4E (0.56) | ALDH1A1KDM4ERAB9ASMN1; SMN2TP53 | |
| SCHEMBL11903539 | 0.80 | TRPV1 (0.57) | ALDH1A1KDM4ERAB9ASMN1; SMN2TP53 | |
| SCHEMBL11903481 | 0.79 | TRPV1 (0.72) | ALDH1A1KDM4ERAB9ASMN1; SMN2TP53 | |
| SCHEMBL12082222 | 0.75 | RAB9A (0.69) | ALDH1A1KDM4ERAB9ASMN1; SMN2TP53 | |
| SCHEMBL28601354 | 0.75 | ALDH1A1 (1.00) | ALDH1A1KDM4ERAB9ASMN1; SMN2TP53 | |
| SCHEMBL2248581 | 0.75 | KDM4E (0.69) | ALDH1A1KDM4ERAB9ASMN1; SMN2TP53 | |
| SCHEMBL11903468 | 0.75 | TRPV1 (0.74) | ALDH1A1KDM4ERAB9ASMN1; SMN2TP53 | |
| SCHEMBL11903471 | 0.74 | P2RY6 (0.67) | ALDH1A1KDM4ERAB9ASMN1; SMN2TP53 | |
| SCHEMBL11903652 | 0.74 | TRPV1 (0.77) | ALDH1A1KDM4ERAB9ASMN1; SMN2TP53 | |
| SCHEMBL11903498 | 0.74 | TRPV1 (0.77) | ALDH1A1KDM4ERAB9ASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8293780-B1 | Anti-cancer agents based on 6-trifluoromethoxybenzimidazole derivatives and method of making | U.S. DEPARTMENT OF ENERGY (US) | 2012-10-23 | — | — | US | disclosed |
| US-8242284-B1 | Anti-cancer agents based on 6-trifluoromethoxybenzimidazole derivatives and method of making | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) | 2012-08-14 | — | — | US | disclosed |