SCHEMBL1190705

SCHEMBL1190705

Cc1cc(C)cc(O[C]=O)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
TSHR P16473 3/20 0.46
CYP3A4 P08684 1/20 0.46
MAPK1 P28482 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.38
NPSR1 Q6W5P4 1/20 0.34
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
LMNA P02545 1/20 0.33
MAOA P21397 1/20 0.33
SLC6A2 P23975 1/20 0.33
TPMT P51580 1/20 0.33
RECQL P46063 1/20 0.33
HSD17B10 Q99714 1/20 0.33
POLB P06746 2/20 0.32
CYP2C9 P11712 1/20 0.32
CA1 P00915 1/20 0.32
CA9 Q16790 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL97382 0.84 ALDH1A1 (0.34) ALDH1A1TSHRCYP3A4MAPK1TDP1
SCHEMBL2094066 0.77 TUBB1 (0.32) CYP3A4MAPK1TDP1POLB
SCHEMBL98118 0.77 ACHE (0.56) ALDH1A1TDP1KMT2ALMNAMAPT
SCHEMBL2092734 0.74 ALDH1A1 (0.58) ALDH1A1CYP3A4KMT2AMEN1POLB
SCHEMBL95901 0.74 ACHE (0.48) ALDH1A1TSHRCYP3A4TDP1SMN1; SMN2
SCHEMBL11866357 0.74 ALDH1A1 (0.41) ALDH1A1TSHRCYP3A4MAPK1TDP1
Carbon Dioxide SCHEMBL28275984 0.73 ALDH1A1 (0.50) ALDH1A1TSHRCYP3A4MAPK1TDP1
SCHEMBL28135369 0.73 ALDH1A1 (0.50) ALDH1A1TSHRCYP3A4MAPK1TDP1
SCHEMBL2096116 0.72 RAPGEF4 (0.35) ALDH1A1TSHRCYP3A4MAPK1TDP1
SCHEMBL2496298 0.70 CYP2A6 (0.54) ALDH1A1TSHRCYP3A4TDP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 288 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4387954-A1 LONG-LIVED REDOX-ACTIVE MOLECULES WITH LOW REDOX POTENTIAL President and Fellows of Harvard College (US) 2024-06-26 EP disclosed
US-20240165267-A1 MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF ARES CAPITAL CORPORATION, AS AGENT 2024-05-23 US disclosed
US-11987590-B2 Compounds that participate in cooperative binding and uses thereof Revolution Medicines, Inc. (US) 2024-05-21 US disclosed
US-20240136561-A1 ELECTRICAL REGENERATION OF ELECTROLYTES PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2024-04-25 US disclosed
EP-4351662-A1 RADIOIMMUNOCONJUGATES AND CHECKPOINT INHIBITOR COMBINATION THERAPY Fusion Pharmaceuticals Inc. (CA) 2024-04-17 EP disclosed
CN-117794585-A Radioimmunoconjugates and checkpoint inhibitor combination therapies 融合制药公司 2024-03-29 CN disclosed
CN-117603148-A Pharmacokinetic enhancement of difunctional chelates and uses thereof 探针技术开发及商业化中心 2024-02-27 CN disclosed
CN-117482261-A Combination therapy of radioimmunoconjugates and checkpoint inhibitors 融合制药公司 2024-02-02 CN disclosed
EP-4292156-A1 ELECTRICAL REGENERATION OF ELECTROLYTES President and Fellows of Harvard College (US) 2023-12-20 EP disclosed
EP-4289950-A2 MACROCYCLIC COMPOUNDS THAT PARTICIPATE IN COOPERATIVE BINDING AND MEDICAL USES THEREOF Revolution Medicines, Inc. (US) 2023-12-13 EP disclosed
US-5837829-A 9-oximesilyl erythromycin a derivatives ABBOTT LABORATORIES (US) 1998-11-17 US disclosed
EP-0605149-B1 Recording sheet JUJO PAPER CO LTD (JP) 1998-04-22 EP disclosed
US-5719272-A 2'-protected 3'-dimethylamine, 9-etheroxime erythromycin A derivatives ABBOTT LABORATORIES (US) 1998-02-17 US disclosed
WO-1997036913-A1 9-OXIMESILYL ERYTHROMYCIN A DERIVATIVES ABBOTT LABORATORIES (US) 1997-10-09 WO disclosed
WO-1997036912-A1 2'-PROTECTED 3'-DIMETHYLAMINE, 9-ETHEROXIME ERYTHROMYCIN A DERIVATIVES ABBOTT LABORATORIES (US) 1997-10-09 WO disclosed
US-5482913-A CARBONATE TYPE BLOCKED COLOR DEVELOPER, LASER RECORDING NIPPON PAPER INDUSTRIES, CO., LTD. (JP) 1996-01-09 US disclosed
EP-0605149-A2 Recording sheet NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1994-07-06 EP disclosed
EP-0158467-B1 METHOD FOR SELECTIVE METHYLATION OF ERYTHROMYCIN A DERIVATIVES TAISHO PHARMACEUTICAL CO. LTD (JP) 1989-07-05 EP disclosed
US-4672109-A Method for selective methylation of erythromycin A derivatives TAISHO PHARMACEUTICAL CO., LTD. (JP) 1987-06-09 US disclosed
EP-0158467-A2 Method for selective methylation of erythromycin a derivatives TAISHO PHARMACEUTICAL CO. LTD (JP) 1985-10-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11987590-B2 Compounds that participate in cooperative binding and uses thereof CEP170, PIN1, FKBP3 ALDH1A1 4800/4885TSHR 4480/4885CYP3A4 2870/4885
US-20240165267-A1 MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF NSUN2, ADAR, NSUN3 ALDH1A1 1969/4885TSHR 2428/4885CYP3A4 4837/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.