Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2937133 | 0.97 | CYP3A4 (0.33) | CYP3A4TDP1RECQLTSHRMAPT | |
| SCHEMBL1961118 | 0.97 | CYP3A4 (0.33) | CYP3A4TDP1RECQLTSHRMAPT | |
| SCHEMBL6418327 | 0.97 | CYP3A4 (0.33) | CYP3A4TDP1RECQLTSHRMAPT | |
| Ethylene SCHEMBL25418134 | 0.95 | CYP3A4 (0.32) | CYP3A4TDP1RECQLTSHRMAPT | |
| Ethylene Glycol SCHEMBL20135732 | 0.92 | CYP3A4 (0.30) | CYP3A4 | |
| SCHEMBL2937130 | 0.85 | CYP3A4 (0.32) | CYP3A4TDP1TSHRMAPTCACNA1B | |
| Phenol SCHEMBL1777269 | 0.83 | CYP3A4 (0.40) | CYP3A4TSHR | |
| SCHEMBL1081592 | 0.83 | — | — | |
| SCHEMBL87407 | 0.82 | CASP1 (0.36) | CYP3A4TDP1RECQLTSHRMAPT | |
| SCHEMBL87406 | 0.82 | RECQL (0.42) | CYP3A4TDP1RECQLTSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8808464-B2 | Method for removal of a hydrophobic and particulate soil composition | ECOLAB USA INC. (US) | 2014-08-19 | — | — | US | claimed |
| US-8349782-B2 | Hydrophobic and particulate soil removal composition | ECOLAB USA INC. (US) | 2013-01-08 | — | — | US | claimed |
| US-20120208735-A1 | Hydrophobic and Particulate Soil Removal Composition | ECOLAB USA INC. (US) | 2012-08-16 | — | — | US | claimed |
| US-20120204908-A1 | Method for Removal of a Hydrophobic and Particulate Soil Composition | ECOLAB USA INC. (US) | 2012-08-16 | — | — | US | claimed |
| US-8808464-B2 | Method for removal of a hydrophobic and particulate soil composition | ECOLAB USA INC. (US) | 2014-08-19 | — | — | US | disclosed |
| US-8349782-B2 | Hydrophobic and particulate soil removal composition | ECOLAB USA INC. (US) | 2013-01-08 | — | — | US | disclosed |
| US-20120208735-A1 | Hydrophobic and Particulate Soil Removal Composition | ECOLAB USA INC. (US) | 2012-08-16 | — | — | US | disclosed |
| US-20120204908-A1 | Method for Removal of a Hydrophobic and Particulate Soil Composition | ECOLAB USA INC. (US) | 2012-08-16 | — | — | US | disclosed |