Ethylene Glycol

Ethylene Glycol

SCHEMBL20135732

C=CCOC(=O)C(CC(=O)[O-])S(=O)(=O)O.OCCO.[Na+]

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Ethylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1961118 0.95 CYP3A4 (0.33) CYP3A4
SCHEMBL2937133 0.95 CYP3A4 (0.33) CYP3A4
Ethylene SCHEMBL25418134 0.94 CYP3A4 (0.32) CYP3A4
Potassium Ion SCHEMBL11909775 0.92 CYP3A4 (0.33) CYP3A4
SCHEMBL6418327 0.92 CYP3A4 (0.33) CYP3A4
SCHEMBL2937130 0.84 CYP3A4 (0.32) CYP3A4
Phenol SCHEMBL1777269 0.82 CYP3A4 (0.40) CYP3A4
SCHEMBL1081592 0.82
SCHEMBL1629058 0.79 CA4 (0.33)
SCHEMBL87407 0.78 CASP1 (0.36) CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10590255-B2 Vinyl acetate-ethylene copolymer emulsion and method for producing same WACKER CHEMICALS KOREA INC. (KR) 2020-03-17 US disclosed
EP-3321305-B1 VINYL ACETATE-ETHYLENE COPOLYMER EMULSION AND METHOD FOR PRODUCING SAME WACKER CHEMIE AG (DE) 2019-05-01 EP disclosed
US-20180194921-A1 VINYL ACETATE-ETHYLENE COPOLYMER EMULSION AND METHOD FOR PRODUCING SAME WACKER CHEMIE AG (DE) 2018-07-12 US disclosed
EP-3321305-A1 VINYL ACETATE-ETHYLENE COPOLYMER EMULSION AND METHOD FOR PRODUCING SAME Wacker Chemie AG (DE) 2018-05-16 EP disclosed