Zinterol

Zinterol

SCHEMBL119175

CC(C)(Cc1ccccc1)NCC(O)c1ccc(O)c(NS(C)(=O)=O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 11/20 1.00
ADRB3 P13945 9/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Zinterol SCHEMBL14452736 1.00 ADRB2 (1.00) ADRB2ADRB3
Zinterol SCHEMBL30338438 1.00 ADRB2 (1.00) ADRB2ADRB3
Zinterol SCHEMBL29390397 0.99 ADRB2 (1.00) ADRB2ADRB3
Zinterol SCHEMBL637070 0.99 ADRB2 (1.00) ADRB2ADRB3
Zinterol SCHEMBL1551570 0.92 ADRB2 (0.85) ADRB2ADRB3
Zinterol SCHEMBL11796024 0.92 ADRB2 (0.85) ADRB2ADRB3
SCHEMBL14451873 0.89 ADRB2 (0.81) ADRB2ADRB3
SCHEMBL14620429 0.89 ADRB2 (0.80) ADRB2ADRB3
SCHEMBL12305639 0.89 ADRB2 (0.80) ADRB2ADRB3
SCHEMBL2450164 0.88 ADRB2 (0.79) ADRB2ADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1273 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240398729-A1 Methods and Compositions for the Treatment of Cytoplasmic Glycogen Storage Disorders DUKE UNIVERSITY (US) 2024-12-05 US claimed
EP-4329849-A1 INHALER 3D Engineering Design Limited (GB) 2024-03-06 EP claimed
US-20230158028-A1 COMPOUNDS AND METHODS FOR INDUCING UCP1 EXPRESSION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2023-05-25 US claimed
EP-4132914-A1 COMPOUNDS AND METHODS FOR INDUCING UCP1 EXPRESSION The Regents of the University of California (US) 2023-02-15 EP claimed
WO-2022229665-A1 INHALER 3D Engineering Design Limited (GB) 2022-11-03 WO claimed
EP-3946268-A1 INHALED STATINS AS BRONCHODILATORS TO IMPROVE LUNG FUNCTION IN RESPIRATORY DISEASES The Regents of The University of California (US) 2022-02-09 EP claimed
US-20220034911-A1 METHOD OF MITIGATION OF DEATH FROM EPILEPTIC SEIZURES VEGA JOSE (US) 2022-02-03 US claimed
US-20210338603-A1 COMBINATIONS OF ADRENERGIC RECEPTOR AGONISTS FOR THE TREATMENT OF TYPE 2 DIABETES ATROGI AB (SE) 2021-11-04 US claimed
US-20200315993-A1 COMBINATIONS OF ADRENERGIC RECEPTOR AGONISTS FOR THE TREATMENT OF TYPE 2 DIABETES ATROGI AB (SE) 2020-10-08 US claimed
WO-2020205663-A1 INHALED STATINS AS BRONCHODILATORS TO IMPROVE LUNG FUNCTION IN RESPIRATORY DISEASES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2020-10-08 WO claimed
WO-2006108424-A2 BETA-2 ADRENOCEPTOR AGONISTS FOR TREATING CONNECTIVE TISSUE DISEASES OF THE SKIN ASTION PHARMA A/S (DK) 2006-10-19 WO claimed
US-20060235048-A1 Treatment of connective tissue diseases of the skin ASTION DEVELOPMENT A/S 2006-10-19 US claimed
EP-1613266-A2 METHODS OF TREATING PAIN AND COMPOSITIONS FOR USE THEREFOR Theraquest Biosciences, LLC (US) 2006-01-11 EP claimed
WO-2004091540-A2 METHODS OF TREATING PAIN AND COMPOSITIONS FOR USE THEREFOR THERAQUEST BIOSCIENCES, LLC (US) 2004-10-28 WO claimed
US-20040209850-A1 synergistic mixture of an analgesic ( opioid, NSAID, COX-2 inhibitor, acetaminophen, or tramadol) and a beta adrenergic agonist; faster response and longer duration; reduced gastrointestinal side effects THERAQUEST BIOSCIENCES, LLC 2004-10-21 US claimed
US-6624181-B1 Synergistic combination ALTANA PHARMA AG (DE) 2003-09-23 US claimed
WO-2003075851-A2 COMPOSITIONS AND METHODS FOR THE TREATMENT OF ANORECTAL DISORDERS CELLEGY PHARMACEUTICALS, INC. (US) 2003-09-18 WO claimed
EP-1336602-A1 Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases Scaramuzzino, Giovanni (IT) 2003-08-20 EP claimed
WO-1994008579-A1 β-AGONIST, α1-AGONIST, AND/OR α2-ANTAGONIST TREATMENT OF NEURODEGENERATIVE DISEASES AND CENTRAL NERVOUS SYSTEM TRAUMA NEW YORK UNIVERSITY (US) 1994-04-28 WO claimed
US-3993776-A 2*-HYDROXY-5*-(1-HYDROXY-2-(2-METHYL-1-PHENYL-2 -PROPYLAMINO)ETHYL)METHANE-SULFONANILIDE MEAD JOHNSON & COMPANY (US) 1976-11-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230158028-A1 COMPOUNDS AND METHODS FOR INDUCING UCP1 EXPRESSION TFAM, FABP4, CPT2 ADRB2 88/4885ADRB3 83/4885
US-20200315993-A1 COMBINATIONS OF ADRENERGIC RECEPTOR AGONISTS FOR THE TREATMENT OF TYPE 2 DIABETES ADRB2, ADRB3, ADRA2C ADRB2 1/4885ADRB3 2/4885
US-20060235048-A1 Treatment of connective tissue diseases of the skin ADRB2, ADRB1, ADRA2A ADRB2 1/4885ADRB3 7/4885
US-20210338603-A1 COMBINATIONS OF ADRENERGIC RECEPTOR AGONISTS FOR THE TREATMENT OF TYPE 2 DIABETES ADRB2, ADRB3, ADRA2C ADRB2 1/4885ADRB3 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.