Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | GPR183 | P32249 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1193925 | 0.86 | THRB (0.55) | THRBGPR183POLBHSD17B10ALDH1A1 | |
| SCHEMBL19376073 | 0.78 | POLB (0.56) | THRBGPR183POLBHSD17B10ALDH1A1 | |
| SCHEMBL31657813 | 0.78 | POLB (0.56) | THRBGPR183POLBHSD17B10ALDH1A1 | |
| SCHEMBL3149402 | 0.78 | ALDH1A1 (0.57) | POLBHSD17B10ALDH1A1HPGDKMT2A | |
| SCHEMBL5467759 | 0.76 | KMT2A (0.64) | THRBGPR183POLBHSD17B10ALDH1A1 | |
| SCHEMBL22196923 | 0.75 | KMT2A (0.66) | POLBHSD17B10ALDH1A1HPGDKMT2A | |
| SCHEMBL21255890 | 0.75 | KMT2A (0.66) | POLBHSD17B10ALDH1A1KMT2AMEN1 | |
| SCHEMBL7006650 | 0.74 | MAPK1 (0.65) | THRBHSD17B10ALDH1A1KMT2AMEN1 | |
| SCHEMBL2873071 | 0.74 | MAPK1 (0.65) | THRBHSD17B10ALDH1A1KMT2AMEN1 | |
| SCHEMBL38650907 | 0.74 | ALDH1A1 (0.53) | POLBHSD17B10ALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110046153-A1 | Medicaments | MOTAC NEUROSCIENCE LIMITED (GB) | 2011-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046153-A1 | Medicaments | MTNR1A, SIGMAR1, OPRK1 | THRB 525/4885GPR183 166/4885POLB 3664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.