Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 3/20 | 0.54 |
| ▸ | GBA1 | P04062 | 1/20 | 0.53 |
| ▸ | GHSR | Q92847 | 1/20 | 0.47 |
| ▸ | PLD2 | O14939 | 1/20 | 0.45 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1193938 | 0.90 | NAMPT (0.45) | NPY5RGBA1P2RX7NAMPTMTNR1A | |
| SCHEMBL22170856 | 0.82 | NPY5R (0.61) | NPY5RGBA1GHSRPLD2PLD1 | |
| SCHEMBL17551505 | 0.81 | NPY5R (0.59) | NPY5RGBA1GHSRPLD2PLD1 | |
| SCHEMBL9083616 | 0.78 | GRIN2B (0.56) | NPY5RMEN1KMT2A | |
| SCHEMBL1193950 | 0.76 | GBA1 (0.53) | NPY5RGBA1GHSRPLD2PLD1 | |
| SCHEMBL1193687 | 0.74 | MAPT (0.48) | MTNR1AMTNR1BEPHX2MEN1KMT2A | |
| SCHEMBL366547 | 0.74 | P2RX7 (0.55) | NPY5RGBA1GHSRP2RX7MTNR1A | |
| SCHEMBL12190609 | 0.73 | NPY5R (0.45) | NPY5RGBA1GHSRPLD2PLD1 | |
| SCHEMBL13722291 | 0.73 | NPY5R (0.49) | NPY5RGBA1GHSRPLD2PLD1 | |
| SCHEMBL9568092 | 0.73 | GHSR (0.49) | NPY5RGBA1GHSRPLD2PLD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110046153-A1 | Medicaments | MOTAC NEUROSCIENCE LIMITED (GB) | 2011-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046153-A1 | Medicaments | MTNR1A, SIGMAR1, OPRK1 | NPY5R 630/4885GBA1 384/4885GHSR 133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.