Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRHR | P34981 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 6/20 | 0.34 |
| ▸ | REN | P00797 | 2/20 | 0.34 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.32 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.32 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12070944 | 0.84 | ACE (0.36) | TRHRACERENDPP4 | |
| SCHEMBL12784272 | 0.84 | DPP7 (0.46) | ACERENDPP4 | |
| SCHEMBL7932659 | 0.76 | HTR1A (0.50) | DPP4 | |
| SCHEMBL12771027 | 0.75 | HDAC4 (0.41) | TRHRACEDPP4 | |
| SCHEMBL13766136 | 0.74 | ITGB3 (0.47) | ACE | |
| SCHEMBL20953071 | 0.70 | DPP4 (0.47) | ACEDPP4 | |
| SCHEMBL6381431 | 0.68 | DPP4 (0.43) | DPP4 | |
| Hydrochloric Acid SCHEMBL11330390 | 0.67 | DPP4 (0.57) | DPP4 | |
| SCHEMBL2539994 | 0.65 | DPP4 (0.42) | ACERENDPP4 | |
| SCHEMBL10311685 | 0.65 | ACE (0.49) | ACERENDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2276725-B1 | NEW RUTHENIUM COMPLEXES AS CATALYSTS FOR METATHESIS REACTIONS | HOFFMANN LA ROCHE (CH) | 2012-07-04 | — | — | EP | disclosed |