Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.36 |
| ▸ | REN | P00797 | 3/20 | 0.36 |
| ▸ | TRHR | P34981 | 1/20 | 0.35 |
| ▸ | PEPD | P12955 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12784272 | 0.88 | DPP7 (0.46) | ACERENDPP4 | |
| SCHEMBL11939488 | 0.84 | TRHR (0.35) | ACERENTRHRDPP4 | |
| SCHEMBL7932659 | 0.79 | HTR1A (0.50) | DPP4 | |
| SCHEMBL12771027 | 0.78 | HDAC4 (0.41) | ACETRHRF2DPP4 | |
| SCHEMBL13766136 | 0.77 | ITGB3 (0.47) | ACEF2 | |
| SCHEMBL20953071 | 0.73 | DPP4 (0.47) | ACEDPP4 | |
| SCHEMBL6381431 | 0.70 | DPP4 (0.43) | DPP4 | |
| SCHEMBL29406923 | 0.69 | DPP7 (0.65) | ACEDPP4 | |
| Hydrochloric Acid SCHEMBL11330390 | 0.69 | DPP4 (0.57) | DPP4 | |
| SCHEMBL425457 | 0.68 | DPP4 (0.40) | ACEDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011150190-A2 | HCV INHIBITOR COMPOUNDS AND METHODS OF USE THEREOF | ANACOR PHARMACEUTICALS, INC. (US) | 2011-12-01 | — | — | WO | disclosed |