Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 12/20 | 0.46 |
| ▸ | DPP4 | P27487 | 11/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 8/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 6/20 | 0.46 |
| ▸ | FAP | Q12884 | 5/20 | 0.46 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12070944 | 0.88 | ACE (0.36) | DPP4RENACE | |
| SCHEMBL11939488 | 0.84 | TRHR (0.35) | DPP4RENACE | |
| SCHEMBL29406923 | 0.83 | DPP7 (0.65) | DPP7DPP4DPP8DPP9FAP | |
| Hydrochloric Acid SCHEMBL11330390 | 0.82 | DPP4 (0.57) | DPP7DPP4DPP8DPP9FAP | |
| SCHEMBL22872683 | 0.80 | DPP4 (0.65) | DPP7DPP4DPP8DPP9FAP | |
| SCHEMBL7932659 | 0.79 | HTR1A (0.50) | DPP4 | |
| Hydrochloric Acid SCHEMBL7409750 | 0.79 | DPP4 (0.64) | DPP7DPP4DPP8DPP9FAP | |
| SCHEMBL13071463 | 0.79 | DPP4 (0.39) | DPP7DPP4DPP8DPP9FAP | |
| Bromide SCHEMBL7279605 | 0.79 | DPP4 (0.64) | DPP7DPP4DPP8DPP9FAP | |
| SCHEMBL12771027 | 0.78 | HDAC4 (0.41) | DPP4DPP8ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2305698-A2 | Macrocyclic inhibitors of Hepatitis C virus replication | Intermune, Inc. (US) | 2011-04-06 | — | — | EP | disclosed |