Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 8/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NNMT | P40261 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | WEE1 | P30291 | 1/20 | 0.34 |
| ▸ | MYT1 | Q01538 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12487400 | 0.82 | LMNA (0.45) | LMNAPOLBDPP4DPP8GRM2 | |
| SCHEMBL12641092 | 0.81 | ALOX15 (0.46) | LMNASMN1; SMN2 | |
| SCHEMBL16751985 | 0.80 | LMNA (0.44) | LMNAPOLBDPP4DPP8GRM2 | |
| SCHEMBL13515885 | 0.77 | LMNA (0.41) | LMNAPOLBDPP4DPP8GRM2 | |
| SCHEMBL28565443 | 0.73 | LMNA (0.38) | LMNAPOLBDPP4DPP8GRM2 | |
| SCHEMBL7718641 | 0.73 | LMNA (0.54) | LMNAPOLBGRM2HTTNNMT | |
| SCHEMBL3999989 | 0.72 | NOS3 (0.46) | LMNAPOLBDPP4DPP8GRM2 | |
| SCHEMBL19998979 | 0.72 | NOS3 (0.56) | LMNAPOLBSMN1; SMN2HTT | |
| SCHEMBL3120976 | 0.71 | KDM4E (0.41) | LMNAPOLBDPP4DPP8GRM2 | |
| SCHEMBL11942285 | 0.71 | LMNA (0.42) | LMNAPOLBDPP4DPP8GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116217543-A | Novel CCR3 inhibitor compound and application thereof | 成都康弘药业集团股份有限公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-115768760-A | Quinoxaline derivatives as anti-cancer agents | 阿斯利康(瑞典)有限公司 | 2023-03-07 | — | — | CN | disclosed |
| CN-107912040-B | Pyrrolidine amide compounds as histone demethylase inhibitors | 基因泰克公司 | 2021-04-06 | — | — | CN | disclosed |
| US-8993772-B2 | Process for the preparation of 4-amino-5-fluoro-3-halo-6-(substituted)picolinates | DOW AGROSCIENCES, LLC. (US) | 2015-03-31 | — | — | US | disclosed |
| US-20140206881-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | DOW AGROSCIENCES LLC (US) | 2014-07-24 | — | — | US | disclosed |
| US-8754231-B2 | Process for the preparation of 4-amino-5-fluoro-3-halo-6-(substituted)picolinates | DOW AGROSCIENCES, LLC. (US) | 2014-06-17 | — | — | US | disclosed |
| US-20120190859-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | DOW AGROSCIENCES LLC (US) | 2012-07-26 | — | — | US | disclosed |
| US-7964623-B2 | Tricyclic benzopyrane compound | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 2011-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120190859-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | CYP4F3, CYP4F12, AFF4 | LMNA 2800/4885POLB 2842/4885DPP4 57/4885 |
| US-20140206881-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | CYP4F3, CYP4F12, AFF4 | LMNA 2800/4885POLB 2842/4885DPP4 57/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.