SCHEMBL11962073

SCHEMBL11962073

OC(CNCc1ccccc1)COC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.48
KMT2A Q03164 4/20 0.48
DNM1 Q05193 1/20 0.47
BCHE P06276 5/20 0.45
BACE1 P56817 1/20 0.45
ADRB2 P07550 1/20 0.44
ADRB1 P08588 1/20 0.44
ADRB3 P13945 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26328548 0.83 MEN1 (0.49) MEN1KMT2ADNM1BCHEBACE1
SCHEMBL2111572 0.80 KIF11 (0.50)
SCHEMBL9170630 0.79 ADRB2 (0.45) MEN1KMT2ADNM1BCHEADRB2
SCHEMBL893963 0.78 BCHE (0.63) MEN1KMT2ADNM1BCHEBACE1
SCHEMBL2306548 0.78 MAPT (0.60) MEN1KMT2ADNM1BCHEADRB2
SCHEMBL1327171 0.78 MAPT (0.60) MEN1KMT2ADNM1BCHEADRB2
SCHEMBL17005472 0.78 MAPT (0.60) MEN1KMT2ADNM1BCHEADRB2
SCHEMBL24473808 0.76 CA1 (0.60) DNM1BCHEADRB2ADRB1ADRB3
SCHEMBL6322151 0.76 ADRB1 (0.67) MEN1KMT2AADRB2ADRB1ADRB3
SCHEMBL21759057 0.76 ADRB1 (0.64) MEN1KMT2AADRB2ADRB1ADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10835608-B2 Polymer-carbohydrate conjugates for drug delivery technology LIPOSEUTICALS INC 2020-11-17 US disclosed
EP-3077006-B1 POLYMER-CARBOHYDRATE CONJUGATES FOR DRUG DELIVERY TECHNOLOGY WU NIAN (US) 2020-08-19 EP disclosed
EP-2673000-B1 POLYMER-CARBOHYDRATE-LIPID CONJUGATES WU NIAN (US) 2018-05-16 EP disclosed
US-9175027-B2 Polymer-carbohydrate-lipid conjugates LIPOSEUTICALS, INC. 2015-11-03 US disclosed
US-9175027-B2 Polymer-carbohydrate-lipid conjugates LIPOSEUTICALS, INC. 2015-11-03 US disclosed
WO-2015085173-A1 POLYMER-CARBOHYDRATE CONJUGATES FOR DRUG DELIVERY TECHNOLOGY WU NIAN (US) 2015-06-11 WO disclosed
US-20150157721-A1 POLYMER-CARBOHYDRATE CONJUGATES FOR DRUG DELIVERY TECHNOLOGY LIPOSEUTICALS INC 2015-06-11 US disclosed
US-20150157721-A1 POLYMER-CARBOHYDRATE CONJUGATES FOR DRUG DELIVERY TECHNOLOGY LIPOSEUTICALS INC 2015-06-11 US disclosed
WO-2012109112-A2 POLYMER-CARBOHYDRATE-LIPID CONJUGATES WU NIAN (US) 2012-08-16 WO disclosed
WO-2012109052-A1 POLYMER-CARBOHYDRATE-LIPID CONJUGATES WU NIAN (US) 2012-08-16 WO disclosed
US-20120202890-A1 POLYMER-CARBOHYDRATE-LIPID CONJUGATES WU NIAN (US) 2012-08-09 US disclosed
US-20120202890-A1 POLYMER-CARBOHYDRATE-LIPID CONJUGATES WU NIAN (US) 2012-08-09 US disclosed
US-20120202979-A1 POLYMER-CARBOHYDRATE-LIPID CONJUGATES LIPOSEUTICALS, INC. 2012-08-09 US disclosed
US-20120202979-A1 POLYMER-CARBOHYDRATE-LIPID CONJUGATES LIPOSEUTICALS, INC. 2012-08-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10835608-B2 Polymer-carbohydrate conjugates for drug delivery technology LIPC, FABP4, CETP MEN1 2733/4885KMT2A 1977/4885DNM1 3164/4885
US-20120202890-A1 POLYMER-CARBOHYDRATE-LIPID CONJUGATES LIPC, FUT6, UGCG MEN1 1849/4885KMT2A 1692/4885DNM1 3061/4885
US-20150157721-A1 POLYMER-CARBOHYDRATE CONJUGATES FOR DRUG DELIVERY TECHNOLOGY LIPC, FABP4, CETP MEN1 2733/4885KMT2A 1977/4885DNM1 3164/4885
US-20120202979-A1 POLYMER-CARBOHYDRATE-LIPID CONJUGATES LIPC, FUT6, UGCG MEN1 1849/4885KMT2A 1692/4885DNM1 3061/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.