Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.61 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.47 |
| ▸ | TUBB | P07437 | 4/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10137801 | 0.85 | BCAT2 (0.57) | PDK2MEN1KMT2ASMN1; SMN2LTB4R2 | |
| SCHEMBL3552327 | 0.81 | RXRA (0.48) | MEN1KMT2ASMN1; SMN2LTB4R2BCAT2 | |
| SCHEMBL29466501 | 0.80 | SLC6A3 (0.67) | SLC6A3SLC6A4TUBB4ATUBBTUBA3C | |
| SCHEMBL3905291 | 0.80 | SLC6A3 (0.67) | SLC6A3SLC6A4TUBB4ATUBBTUBA3C | |
| SCHEMBL28231510 | 0.80 | SLC6A3 (0.66) | SLC6A3SLC6A4TUBB4ATUBBTUBA3C | |
| SCHEMBL497304 | 0.78 | SLC6A4 (0.64) | SLC6A3SLC6A4TUBB4ATUBBTUBA3C | |
| SCHEMBL11132172 | 0.78 | SLC6A3 (0.64) | SLC6A3SLC6A4TUBB4ATUBBTUBA3C | |
| Hydrochloric Acid SCHEMBL7605048 | 0.77 | SLC6A4 (0.62) | SLC6A3SLC6A4TUBB4ATUBBTUBA3C | |
| SCHEMBL2567641 | 0.77 | BCAT2 (0.71) | SLC6A3SLC6A4TUBB4ATUBBTUBA3C | |
| SCHEMBL7605043 | 0.77 | SLC6A3 (0.62) | SLC6A3SLC6A4TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014066695-A1 | COMPOSITIONS AND METHODS FOR TREATING ESTROGEN-RELATED MEDICAL DISORDERS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2014-05-01 | — | — | WO | disclosed |
| US-20120214798-A1 | Novel Ethanediamone Hepcidine Antagonists | VIFOR (INTERNATIONAL) AG (CH) | 2012-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120214798-A1 | Novel Ethanediamone Hepcidine Antagonists | HAMP, SLC40A1, FTH1 | SLC6A3 4084/4885SLC6A4 3636/4885TUBB4A 4715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.