Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.70 |
| ▸ | F3 | P13726 | 3/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.70 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | RECQL | P46063 | 2/20 | 0.70 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.70 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | TNKS | O95271 | 1/20 | 0.53 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20518814 | 0.84 | MAPT (1.00) | CYP1A2F3CYP2C9CYP2D6PLIN1 | |
| SCHEMBL28181 | 0.84 | MAPT (1.00) | CYP1A2F3CYP2C9CYP2D6PLIN1 | |
| SCHEMBL478244 | 0.84 | MAPT (1.00) | CYP1A2F3CYP2C9CYP2D6PLIN1 | |
| SCHEMBL22146 | 0.84 | MAPT (1.00) | CYP1A2F3CYP2C9CYP2D6PLIN1 | |
| SCHEMBL20846 | 0.84 | MAPT (1.00) | CYP1A2F3CYP2C9CYP2D6PLIN1 | |
| SCHEMBL5347650 | 0.84 | MAPT (1.00) | CYP1A2F3CYP2C9CYP2D6PLIN1 | |
| SCHEMBL28435740 | 0.84 | MAPT (1.00) | CYP1A2F3CYP2C9CYP2D6PLIN1 | |
| SCHEMBL20856054 | 0.84 | MAPT (1.00) | CYP1A2F3CYP2C9CYP2D6PLIN1 | |
| SCHEMBL14832106 | 0.82 | MAPT (0.95) | CYP1A2F3CYP2C9CYP2D6PLIN1 | |
| SCHEMBL21879664 | 0.82 | MAPT (0.95) | CYP1A2F3CYP2C9CYP2D6PLIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9174960-B2 | Compounds useful against kinetoplastideae parasites | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2015-11-03 | — | — | US | disclosed |
| US-20120214996-A1 | COMPOUNDS USEFUL AGAINST KINETOPLASTIDEAE PARASITES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120214996-A1 | COMPOUNDS USEFUL AGAINST KINETOPLASTIDEAE PARASITES | TST, PDXK, TBCB | CYP1A2 1796/4885F3 3037/4885CYP2C9 3064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.