Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 2/20 | 0.32 |
| ▸ | RHOC | P08134 | 2/20 | 0.32 |
| ▸ | RHOA | P61586 | 2/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22919822 | 1.00 | PTGES (0.33) | PTGESCCR2RHOCRHOARXRA | |
| Fluralaner SCHEMBL121934 | 0.94 | CA1 (0.32) | PTGESHDAC4KDM4E | |
| Fluralaner SCHEMBL29362559 | 0.94 | CA1 (0.32) | PTGESHDAC4KDM4E | |
| Fluralaner SCHEMBL29399660 | 0.94 | CA1 (0.32) | PTGESHDAC4KDM4E | |
| Fluralaner SCHEMBL8515337 | 0.94 | CA1 (0.32) | PTGESHDAC4KDM4E | |
| Fluralaner SCHEMBL8513367 | 0.94 | CA1 (0.32) | PTGESHDAC4KDM4E | |
| Afoxolaner SCHEMBL15741754 | 0.93 | PTGES (0.30) | PTGESCCR2TP53 | |
| SCHEMBL23546689 | 0.92 | GABRA5 (0.31) | PTGES | |
| SCHEMBL23547563 | 0.91 | CCR2 (0.32) | CCR2RXRARXRBTP53HDAC4 | |
| SCHEMBL31743015 | 0.91 | CCR2 (0.32) | CCR2RXRARXRBTP53HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 196 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3646731-A1 | PESTICIDAL MIXTURES COMPRISING A PYRAZOLE COMPOUND | BASF SE (DE) | 2020-05-06 | — | — | EP | claimed |
| EP-3300602-B1 | PESTICIDAL MIXTURES COMPRISING A PYRAZOLE COMPOUND | BASF SE (DE) | 2020-03-25 | — | — | EP | claimed |
| EP-3300602-A1 | PESTICIDAL MIXTURES COMPRISING A PYRAZOLE COMPOUND | BASF SE (DE) | 2018-04-04 | — | — | EP | claimed |
| US-20160219872-A1 | Foamable Pesticide Compositions And Methods Of Application | BASF CORPORATION | 2016-08-04 | — | — | US | claimed |
| US-9339030-B2 | Foamable pesticide compositions and methods of application | BASF CORPORATION (US) | 2016-05-17 | — | — | US | claimed |
| EP-2864320-A1 | PYRAZOLE COMPOUND AND PESTICIDAL MIXTURES COMPRISING A PYRAZOLE COMPOUND | BASF SE (DE) | 2015-04-29 | — | — | EP | claimed |
| US-20150105258-A1 | Methods For Controlling Pests | BASF CORPORATION (US) | 2015-04-16 | — | — | US | claimed |
| US-8980294-B2 | Methods for controlling pests | BASF CORPORATION (US) | 2015-03-17 | — | — | US | claimed |
| US-8940662-B2 | Methods for controlling pests | BASF CORPORATION (US) | 2015-01-27 | — | — | US | claimed |
| WO-2014063942-A1 | SUBSTITUTED PESTICIDAL PYRAZOLE COMPOUNDS | BASF SE (DE) | 2014-05-01 | — | — | WO | claimed |
| US-20120149570-A1 | Foamable Pesticide Compositions And Methods Of Application | BASF CORPORATION (US) | 2012-06-14 | — | — | US | claimed |
| EP-2424370-A2 | FOAMABLE PESTICIDE COMPOSITIONS | BASF Corporation (US) | 2012-03-07 | — | — | EP | claimed |
| EP-2424347-A1 | PESTICIDE COMPOSITIONS AND APPLICATORS | BASF Corporation (US) | 2012-03-07 | — | — | EP | claimed |
| WO-2011147952-A1 | PESTICIDAL MIXTURES | BASF SE (DE) | 2011-12-01 | — | — | WO | claimed |
| WO-2011025789-A2 | FOAMABLE PESTICIDE COMPOSITIONS AND METHODS OF APPLICATION | BASF CORPORATION (US) | 2011-03-03 | — | — | WO | claimed |
| US-20100322892-A1 | PESTICIDE COMPOSITIONS AND APPLICATORS | BASF CORPORATION (US) | 2010-12-23 | — | — | US | claimed |
| US-20100323897-A1 | FOAMABLE PESTICIDE COMPOSITIONS | BASF CORPORATION (US) | 2010-12-23 | — | — | US | claimed |
| US-20100322990-A1 | METHODS FOR CONTROLLING PESTS | BASF CORPORATION (US) | 2010-12-23 | — | — | US | claimed |
| WO-2010129345-A2 | FOAMABLE PESTICIDE COMPOSITIONS | BASF CORPORATION (US) | 2010-11-11 | — | — | WO | claimed |
| WO-2010127019-A1 | PESTICIDE COMPOSITIONS AND APPLICATORS | BASF CORPORATION (US) | 2010-11-04 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149570-A1 | Foamable Pesticide Compositions And Methods Of Application | DDT, PLD1, ACHE | PTGES 1237/4885CCR2 935/4885RHOC 122/4885 |
| US-20100323897-A1 | FOAMABLE PESTICIDE COMPOSITIONS | DDT, PON1, ACHE | PTGES 1994/4885CCR2 849/4885RHOC 367/4885 |
| US-20100322990-A1 | METHODS FOR CONTROLLING PESTS | DDT, ACHE, PON1 | PTGES 2010/4885CCR2 1402/4885RHOC 145/4885 |
| US-20100322892-A1 | PESTICIDE COMPOSITIONS AND APPLICATORS | DDT, ACHE, CHRM2 | PTGES 3958/4885CCR2 241/4885RHOC 284/4885 |
| US-20150105258-A1 | Methods For Controlling Pests | DDT, ACHE, PON1 | PTGES 2010/4885CCR2 1402/4885RHOC 145/4885 |
| US-20160219872-A1 | Foamable Pesticide Compositions And Methods Of Application | DDT, PLD1, ACHE | PTGES 1237/4885CCR2 935/4885RHOC 122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.