Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 5/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 5/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 5/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19316649 | 0.87 | TSHR (0.39) | SCN1ASCN2ASCN3APTGS2TSHR | |
| SCHEMBL12019253 | 0.84 | TSHR (0.40) | PTGS2TSHRKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL16127934 | 0.83 | SCN1A (0.40) | SCN1ASCN2ASCN3ACHRNB2CHRNB4 | |
| SCHEMBL12018013 | 0.82 | SCN1A (0.48) | SCN1ASCN2ASCN3ACHRNB2CHRNB4 | |
| SCHEMBL19316666 | 0.82 | TSHR (0.40) | PTGS2TSHRMEN1KMT2ALMNA | |
| SCHEMBL19316647 | 0.82 | TSHR (0.39) | SCN1ASCN2ASCN3ATSHRMEN1 | |
| SCHEMBL172229 | 0.82 | ADRB2 (0.45) | TSHRMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL12018014 | 0.81 | SCN1A (0.45) | SCN1ASCN2ASCN3ACHRNB2CHRNB4 | |
| SCHEMBL9615565 | 0.81 | ALDH1A1 (0.45) | PTGS2TSHRLMNAALDH1A1 | |
| SCHEMBL12018023 | 0.80 | CHRNB2 (0.49) | SCN1ASCN2ASCN3ACHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120219885-A1 | NOVEL NON-CRYSTALLIZING METHACRYLATES, PRODUCTION AND USE THEREOF | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2012-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120219885-A1 | NOVEL NON-CRYSTALLIZING METHACRYLATES, PRODUCTION AND USE THEREOF | MEP1A, MMAB, RHOA | SCN1A 4349/4885SCN2A 4042/4885SCN3A 4263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.