Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 5/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 5/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 5/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | BRS3 | P32247 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20885165 | 0.85 | MTNR1A (0.33) | KMT2A | |
| SCHEMBL16127811 | 0.84 | L3MBTL1 (0.38) | MEN1KMT2ALMNA | |
| SCHEMBL12019252 | 0.83 | SCN1A (0.47) | SCN1ASCN2ASCN3ACHRNB2CHRNB4 | |
| SCHEMBL22213482 | 0.80 | L3MBTL1 (0.35) | MEN1KMT2ALMNA | |
| SCHEMBL18272058 | 0.79 | CHRM3 (0.38) | MEN1KMT2ALMNA | |
| SCHEMBL18269756 | 0.79 | LMNA (0.42) | SCN1ASCN2ASCN3AMEN1KMT2A | |
| SCHEMBL11920353 | 0.79 | AR (0.41) | MEN1KMT2ALMNAPOLB | |
| SCHEMBL16127962 | 0.78 | ADRB2 (0.39) | KMT2ASMN1; SMN2LMNAPOLB | |
| SCHEMBL15894730 | 0.78 | PTPN1 (0.38) | TSHRPOLB | |
| SCHEMBL11920352 | 0.78 | TSHR (0.44) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2976323-B1 | HIGH REFRACTIVE INDEX ADDITION-FRAGMENTATION AGENTS | 3M INNOVATIVE PROPERTIES CO (US) | 2020-07-15 | — | — | EP | disclosed |
| US-20190105237-A1 | HIGH REFRACTIVE INDEX ADDITION-FRAGMENTATION AGENTS | 3M INNOVATIVE PROPERTIES CO (US) | 2019-04-11 | — | — | US | disclosed |
| US-10195119-B2 | High refractive index addition-fragmentation agents | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2019-02-05 | — | — | US | disclosed |
| US-20160279033-A1 | HIGH REFRACTIVE INDEX ADDITION-FRAGMENTATION AGENTS | 3M INNOVATIVE PROPERTIES COMPANY | 2016-09-29 | — | — | US | disclosed |
| US-20160279033-A1 | HIGH REFRACTIVE INDEX ADDITION-FRAGMENTATION AGENTS | 3M INNOVATIVE PROPERTIES COMPANY | 2016-09-29 | — | — | US | disclosed |
| WO-2014151363-A1 | HIGH REFRACTIVE INDEX ADDITION-FRAGMENTATION AGENTS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10195119-B2 | High refractive index addition-fragmentation agents | EEF1G, FANCI, EEF1E1 | SCN1A 4073/4885SCN2A 4139/4885SCN3A 3956/4885 |
| US-20160279033-A1 | HIGH REFRACTIVE INDEX ADDITION-FRAGMENTATION AGENTS | EEF1G, FANCI, EEF1E1 | SCN1A 4073/4885SCN2A 4139/4885SCN3A 3956/4885 |
| US-20190105237-A1 | HIGH REFRACTIVE INDEX ADDITION-FRAGMENTATION AGENTS | EEF1G, FANCI, EEF1E1 | SCN1A 4073/4885SCN2A 4139/4885SCN3A 3956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.